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BioWorld - Sunday, December 21, 2025
Home » Topics » Disease categories and therapies » Diabetes

Diabetes
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Scientists shaking hands in the lab

International consensus on ketone monitoring emerges

Dec. 11, 2025
By Annette Boyle
The first international consensus framework for the use of continuous ketone monitoring in people with diabetes, published in The Lancet Diabetes & Endocrinology, calls development and use of ketone sensors for the prevention of diabetic ketoacidosis “transformational.” Several companies in the diabetes technology market have recently reported that they are developing dual glucose-ketone sensors, though none have gained U.S. FDA approval yet.
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3-30-fractyl-revita.png

Fractyl procedure sustains weight loss after GLP-1s

Dec. 2, 2025
By Annette Boyle
Glucagon-like peptide-1 (GLP-1) receptor agonists clearly help patients shed pounds, but many regain all - or more - of the weight once they discontinue the medications. Fractyl Health Inc. could offer an enduring solution with its Revita procedure. Six-month results from its open-label REVEAL-1 cohort of individuals with obesity who lost 15% or more of their total body weight on a GLP-1 therapy maintained that loss after discontinuing the drugs and undergoing the Revita procedure.
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Medicare puzzle

Medicare’s competitive bidding program draws opposition

Dec. 2, 2025
By Mark McCarty
The U.S. Centers for Medicare & Medicaid Services has posted the home health final rule for calendar year 2026 and has established a framework for competitive bidding for products such as continuous glucose monitors, a move that is struggling to find support among stakeholders.
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Medicare puzzle

OIG sees potential for savings in Medicare CGM coverage

Nov. 26, 2025
By Mark McCarty
The Office of Inspector General issued a report stating that the Medicare program could save “tens of millions of dollars” in a single year on continuous glucose monitors and associated supplies if the Centers for Medicare & Medicaid Services acted to apply price pressure on suppliers.
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South Korean won

Cha Group to Acquire Majority Stake in Kakao Healthcare

Nov. 25, 2025
By Marian (YoonJee) Chu
Kakao Healthcare Corp. plans to secure ₩100 billion (US$68 million) through two investment deals with Cha Biomedical Group and outside investors by early next year. The transactions, expected to close by the first quarter of 2026, will make Cha the controlling shareholder of Kakao Healthcare with a 43.08% stake. Kakao Corp., the parent company, will hold 29.99%, and external investors will own 26.93%.
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CMS logo and website

CMS terminates Treatment Choices model in ESRD final rule

Nov. 25, 2025
By Mark McCarty
The U.S. Centers for Medicare & Medicaid Services ended the Treatment Choices model under the end stage renal disease payment payment system for several reasons, including its failure to deliver meaningful savings.
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Dexcom G7 CGM

FDA clears Dexcom Smart Basal for insulin optimization

Nov. 19, 2025
By Annette Boyle
Dexcom Inc. received U.S. FDA clearance for its Smart Basal CGM-integrated basal insulin dosing optimizer. Designed for adults with type 2 diabetes using glargine U-100 long-acting insulin therapy, Smart Basal uses data from Dexcom’s G7 15 Day sensor with doses logged by the user to personalize recommendations and adjust long-acting insulin doses, with direction from the patient’s health care provider.
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Dexcom G7 CGM

Halloween turns scary for Dexcom despite strong Q3

Oct. 31, 2025
By Annette Boyle
Dexcom Inc. executives may have thought a $30 million beat of the consensus estimates for third quarter revenue and 20% year-over-year organic growth provided a treat to shareholders, but investors seemed to feel tricked instead. The continuous glucose monitoring powerhouse saw its share price drop a frightening 17% in the first two hours of trading on Oct. 31, pushing it down by one-third from its peak of $89.53 in late July. Investors appear to have been spooked by the company’s conservative projections for 2026, following issues with its G7 sensor, which management said have been largely resolved.
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Insulin pen

Adocia’s Biochaperone Lispro phase III T1D data positive in China

Oct. 28, 2025
By Marian (YoonJee) Chu
No Comments
Adocia SA is looking to further apply its Biochaperone formulation technology to metabolic disorders, Olivier Soula, Adocia co-founder and CEO told BioWorld, the firm having recently gained positive top-line phase III results of Tonghua Dongbao Pharmaceutical Co. Ltd.’s THDB-0206 injection (Biochaperone Lispro) in diabetes patients in China.
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Insulin pen

Adocia’s Biochaperone Lispro phase III T1D data positive in China

Oct. 24, 2025
By Marian (YoonJee) Chu
No Comments
Adocia SA is looking to further apply its Biochaperone formulation technology to metabolic disorders, Olivier Soula, Adocia co-founder and CEO told BioWorld, the firm having recently gained positive top-line phase III results of Tonghua Dongbao Pharmaceutical Co. Ltd.’s THDB-0206 injection (Biochaperone Lispro) in diabetes patients in China.
Read More
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