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BioWorld - Monday, July 20, 2026
Home » Topics » Disease categories and therapies » Endocrine/metabolic

Endocrine/metabolic
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BIO Asia-Taiwan 2026

Capital remains selective in ‘barbell’ biotech market

July 16, 2026
By Marian (YoonJee) Chu
No Comments
Signs of recovery are emerging in the biotechnology investment sector, although investors across Asia say that capital is flowing selectively to companies that can demonstrate clinical differentiation, strong management teams and a clear path to commercialization.
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Illustration of lipids in the bloodstream
Endocrine/metabolic

Fosun cleared to conduct clinical trials with FXR-0906

July 16, 2026
No Comments
Fosun Pharma subsidiary Fosun Pharmaceutical Industrial Development (Shenzhen) Co. Ltd. has received approval from China’s National Medical Products Administration (NMPA) to commence clinical trials for FXR-0906 for the treatment of hypertriglyceridemia.
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Doctor points at molecular structure
Endocrine/metabolic

Ascletis to develop fixed-dose combination of ASC-48 and ASC-30

July 16, 2026
No Comments
Ascletis Pharma Inc. has selected a fixed-dose combination of ASC-48, an oral small-molecule glucose-dependent insulinotropic polypeptide receptor (GIPR) agonist, and ASC-30, an oral small-molecule glucagon-like peptide 1 receptor (GLP-1R) agonist, for clinical development for obesity.
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China’s Mindrank raises $52M series B to advance oral GLP-1

July 14, 2026
By Tamra Sami
No Comments
Mindrank AI Ltd. completed a $52 million series B round to advance MDR-001, its AI-discovered oral small-molecule GLP-1 receptor agonist, which is in phase III trials for obesity in China.
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Endocrine/metabolic

Shanghai Institute of Materia Medica patents new lipid-lowering gluconeogenesis inhibitors

July 14, 2026
Shanghai Institute of Materia Medica of the Chinese Academy of Sciences has disclosed new compounds acting as lipid-lowering agents and gluconeogenesis inhibitors potentially useful for the treatment of metabolic diseases.
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Photo of scale with woman sitting on floor holding head and arms on knees
Neurology/psychiatric

Rethinking anorexia: A disorder of mind and metabolism

July 14, 2026
By Coia Dulsat
No Comments
Anorexia nervosa (AN) is a complex and severe eating disorder that has long been considered a psychiatric condition driven by distorted body image and maladaptive eating behaviors. No effective therapy is currently available. At a symposium held during the recent FENS Forum in Barcelona, several leading researchers with decades of experience in AN presented findings that further strengthen the growing body of evidence supporting the disorder’s metabolic component.
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Blue digital dollar sign

China’s Mindrank raises $52M series B to advance oral GLP-1

July 13, 2026
By Tamra Sami
No Comments
Mindrank AI Ltd. completed a $52 million series B round to advance MDR-001, its AI-discovered oral small-molecule GLP-1 receptor agonist, which is in phase III trials for obesity in China.
Read More
Endocrine/metabolic

Shenzhen Linggene Biotechnology discloses new OGT degradation inducers

July 13, 2026
Shenzhen Linggene Biotechnology Co. Ltd. has synthesized new proteolysis targeting chimera (PROTAC) compounds comprising an E3 ubiquitin ligase-binding agent coupled to a UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase (OGT)-targeting moiety acting as OGT degradation inducers.
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Illustration of bacteria, microorganisms in the gastrointestinal system

Microbial ecology reshapes cancer care, diagnostics and therapies

July 10, 2026
By Mar de Miguel
No Comments
Cancer researchers are increasingly turning to the microbiome to understand why some patients respond well to treatment while others face severe complications. Gut microbial communities shift during intensive therapies such as bone marrow transplantation, and those changes influence infection risk, immune recovery and long‑term survival. New advances in microbial sequencing and engineering redefine this community as a measurable clinical parameter that can be monitored, modeled, and even therapeutically reshaped to improve outcomes in oncology and other conditions.
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Illustration of pill being analyzed
Endocrine/metabolic

Rani collaborates with Pegbio on oral drug delivery in obesity

July 10, 2026
No Comments
Rani Therapeutics Holding Inc. has entered into a research and development collaboration with Pegbio Co. Ltd. to explore the delivery of multiple candidates from Pegbio’s obesity and metabolic disease pipeline using Rani’s proprietary Ranipill platform.
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