A high-density lipoprotein (HDL) subspecies produced by small intestine, which potently shields the endotoxicity of bacterial lipopolysaccharide (LPS), may protect against gut-derived liver injury, according to a study led by scientists at Washington University School of Medicine (WUSM) in St. Louis.
Differences between Seres Therapeutics Inc.’s next-generation microbiome therapy and SER-287 were highlighted in the wake of the phase IIb failure with the latter in the study called Eco-Reset, which missed its primary endpoint of improving clinical remission rates in ulcerative colitis (UC) compared to placebo.
RSS
