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BioWorld - Wednesday, February 4, 2026
Home » Topics » Disease categories and therapies » Infection

Infection
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Elderly person receiving shot

GSK posts strong results for RSV shot, as Pfizer prepares to file rival shot

Oct. 13, 2022
By Richard Staines
GSK plc has announced results from its respiratory syncytial virus (RSV) vaccine in older people that look stronger than those from its rival, Pfizer Inc., as the race to develop a first ever vaccine against the common respiratory disease heats up.
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‘SOFA’ so good: Inotrem’s nangibotide improves organ function in phase IIb septic shock study

Oct. 13, 2022
By Cormac Sheridan
A phase IIb trial of nangibotide in septic shock has demonstrated preliminary signs of efficacy in a subset of biomarker-defined patients and provided its developer, Inotrem SA, with a dataset that will inform the design of a registration program for the drug. Subject to agreement from regulatory agencies, the company aims to move the triggering receptor on myeloid cells 1 inhibitor into a first phase III trial in early 2024. “We should have a clearer picture by the beginning of the second next year,” CEO Sven Zimmermann told BioWorld.
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CSL’s Seqirus snags $30M contract with BARDA to develop pandemic avian flu vaccines

Oct. 11, 2022
By Tamra Sami
CSL Ltd. subsidiary Seqirus inked a $30.1 million deal with the U.S. Biomedical Advanced Research and Development Authority (BARDA) to develop and evaluate two influenza A subtype H2Nx (avian flu) vaccines in a phase I trial.
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CSL’s Seqirus snags $30M contract with BARDA to develop pandemic avian flu vaccines

Oct. 10, 2022
By Tamra Sami
CSL Ltd. subsidiary Seqirus inked a $30.1 million deal with the U.S. Biomedical Advanced Research and Development Authority (BARDA) to develop and evaluate two influenza A subtype H2Nx (avian flu) vaccines in a phase I trial.
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Influenza virus
Immune

A universal influenza vaccine candidate provides broad protection in young and aged mice

Oct. 10, 2022
Finding a vaccine that provides universal protection against seasonal influenza remains a public health priority. Although influenza neuraminidase (NA) undergoes slower antigenic changes than hemagglutinin (HA) and therefore constitutes a desirable vaccine target, NA standalone vaccination strategies present a limited breadth of NA immunity.
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Novel coronavirus SARS-CoV-2 spike protein
Infection

Sorrento publishes data on STI-5041 MAb against SARS-CoV-2 spike protein

Oct. 10, 2022
Sorrento Therapeutics Inc. has published data on the identification, in vitro binding and neutralizing activity of a novel monoclonal antibody (MAb), STI-5041, against the SARS-CoV-2 WA-1 strain as well as the alpha and beta variants from their G-MAB library screening.
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Infection

University of Arizona patents SARS-CoV-2 Nsp3 inhibitors

Oct. 7, 2022
The University of Arizona has divulged nonstructural protein 3 (Nsp3; PL-PRO) (SARS-CoV-2; COVID-19 virus) inhibitors reported to be useful for the treatment of SARS-CoV-2 infection.
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Immune

CEPI awards funding to Intravacc to advance betacoronavirus vaccine candidate

Oct. 7, 2022
CEPI, the Coalition for Epidemic Preparedness Innovations, will provide seed funding of up to $4.8 million to Intravacc BV to advance the development of a broadly protective betacoronavirus vaccine candidate, which can be delivered intranasally.
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Infection

Covira closes dilutive funding to advance microbiome therapy to prevent postsurgical infections

Oct. 7, 2022
Covira Inc., a spinout from The University of Chicago, has closed its first dilutive funding via an oversubscribed $1.0 million seed round after raising $9.1 million of nondilutive funding.
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Antibiotic resistant bacteria inside a biofilm
Infection

Revelation Biosciences enters license agreement with Vanderbilt on PHAD for infections

Oct. 7, 2022
Revelation Biosciences Inc. has entered into an exclusive worldwide license agreement with Vanderbilt University to develop and commercialize phosphorylated hexaacyl disaccharide (PHAD) for treating or preventing infections.
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