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BioWorld - Tuesday, April 14, 2026
Home » Topics » Disease categories and therapies » Infection

Infection
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Infection

University of Colorado presents new efflux pump inhibitors for bacterial infections

March 1, 2024
University of Colorado has divulged efflux pump (bacterial) inhibitors reported to be useful for the treatment of bacterial infections, particularly, gram-negative bacterial infections.
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Infection

Macquarie University describes new 3CLpro inhibitors to treat SARS-CoV-2 infection

March 1, 2024
Macquarie University has identified 3C-like proteinase (3CLpro; Mpro; nsp5) (SARS-CoV-2; COVID-19 virus) inhibitors reported to be useful for the treatment of SARS-CoV-2 infection (COVID-19).
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Creative rendition of SARS-CoV-2 virus particles.
Immune

Imunon reports findings with IMNN-101 from live virus challenge study against SARS-CoV-2 variant XBB.1.5

March 1, 2024
Imunon Inc. has released promising results from a live virus challenge study conducted by the Wistar Institute with IMNN-101 against the SARS-CoV-2 variant XBB.1.5. This study was conducted using the clinical vector that Imunon intends to bring into its phase I study during the second quarter, and showed IMNN-101 immunogenicity and protective activity in a live viral mouse challenge.
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Antibodies attacking virus cell
BioWorld Infectious Disease Index (BIDI)

BioWorld Infectious Disease Index closes 2023 down 43%

Feb. 29, 2024
By Amanda Lanier
In 2023, the BioWorld Infectious Disease Index (BIDI) concluded with a 43.48% decline, showing improvement from the 83.57% drop observed in 2022. While an uptick was seen from October's year-to-date performance, down 47.98%, BIDI still lagged both the Nasdaq Biotechnology Index and the Dow Jones Industrial Average for the year, which saw gains of 3.74% and 13.7%, respectively.
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Infection

Avitar Biosciences presents new 3CLpro inhibitors to treat SARS-CoV-2 infection

Feb. 29, 2024
Avitar Biosciences Inc. has divulged 3C-like proteinase (3CLpro; Mpro; nsp5) (SARS-CoV-2; COVID-19 virus) inhibitors reported to be useful for the treatment of SARS-CoV-2 infection (COVID-19).
Read More
Illustration of E. coli with window showing DNA
Immune

CARB-X award supports carb-targeting neonatal sepsis vaccine

Feb. 29, 2024
Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator (CARB-X) is awarding Glyprovac LLC US$467,000 to develop a maternal vaccine that targets Escherichia coli, a bacterial species responsible for a large portion of neonatal sepsis infections.
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Colorized transmission electron micrograph of rabies virus particles (teal) next to an image of a lone wandering dog.
Immune

Dyadic and Rabian collaborate on rabies prophylactics and vaccines

Feb. 29, 2024
Dyadic International Inc.'s Dutch subsidiary, Dyadic Nederland BV, has entered into a strategic partnership agreement and collaboration with Rabian BV to develop efficacious, scalable, and affordable rabies prophylactics and vaccines utilizing Dyadic's C1 protein production platform.
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Takeda, Biological E. partner to widen global access to Qdenga

Feb. 28, 2024
By Tamra Sami
In a move to widen global access to its Qdenga dengue vaccine, Takeda Pharmaceutical Co. Ltd. is partnering with India’s Biological E. Ltd. to manufacture Qdenga (TAK-003).
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Allecra’s Exblifep crosses finish line first with FDA nod in UTIs

Feb. 27, 2024
By Jennifer Boggs
Allecra Therapeutics GmbH secured U.S. FDA approval for its beta-lactam/beta-lactamase inhibitor combination, Exblifep (cefepime/enmetazobactam), in complicated urinary tract infections, including pyelonephritis, in patients 18 years and older.
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Vaccine and data illustration
Newco news

Baseimmune raises $11.3M to advance mutation-resistant vaccines

Feb. 27, 2024
By Caroline Richards
Baseimmune Ltd. has raised $11.3 million through a series A to accelerate the development of its deep learning AI technology for predicting future pathogen mutations to generate a series of longer-lasting, multistrain vaccines.
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