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BioWorld - Thursday, February 26, 2026
Home » Topics » Disease categories and therapies » Respiratory

Respiratory
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Gene editing illustration
Respiratory

Intellia and Recode collaborate on genomic medicines for cystic fibrosis

Feb. 16, 2024
Intellia Therapeutics Inc. and Recode Therapeutics Inc. have established a strategic collaboration to develop novel genomic medicines for the treatment of cystic fibrosis.
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Respiratory

New DPP4 inhibitors for lung disease disclosed in Scripps Research Institute patent

Feb. 14, 2024
Scripps Research Institute has synthesized dipeptidyl peptidase 4 inhibitors reported to be useful for the treatment of lung diseases.
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Scientist, microscope and dropper
Dermatologic

Attovia Therapeutics to use financing to advance Attobody pipeline

Feb. 9, 2024
Attovia Therapeutics Inc. has announced the closing of the $30 million second tranche of its $60 million series A financing.
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Digital lungs illustration
Respiratory

Anima Biotech’s IPF candidate disrupts transformation of fibroblasts into fully differentiated myofibroblasts

Feb. 8, 2024
Anima Biotech Inc. has released promising preclinical data on its new candidate, which has potential for treating idiopathic pulmonary fibrosis (IPF).
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Lungs
Respiratory

Aatec Medical and SPRIND collaborate to advance ATL-105 for viral respiratory diseases

Feb. 7, 2024
Aatec Medical GmbH has announced the start of its collaboration with the German Federal Agency for Disruptive Innovations (SPRIND), which will help advance the preclinical development of ATL-105.
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Vertex feels no pain in new, head-to-head CF data

Feb. 6, 2024
By Lee Landenberger
Vertex Pharmaceuticals Inc. upped its own ante with pivotal phase III data in its strong suit, cystic fibrosis (CF). Taking on Trikafta, the company’s bestseller, Vertex’s once-daily vanzacaftor/tezacaftor/deutivacaftor (vanza) combo hit all primary and key secondary endpoints in two randomized controlled studies of those ages 12 and older.
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Respiratory

Chiesi Farmaceutici identifies new DPP-1 inhibitors for NCFBE

Feb. 6, 2024
Chiesi Farmaceutici SpA has prepared azetidine derivatives acting as cathepsin C (dipeptidyl peptidase 1, DPP-1) inhibitors and reported to be useful for the treatment of non-cystic fibrosis bronchiectasis (NCFBE), among others.
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Lungs wireframe illustration
Respiratory

Researchers develop robust murine model of vesicant-induced acute lung injury

Feb. 5, 2024
Burn injuries, including those induced by chemicals, may have systemic effects, and can lead to acute lung injury (ALI). Chemical burn injuries account for about 2% to 5% of total skin burn injuries. Among the chemicals, vesicating agents like Lewisite are particularly relevant due to the lack of antidotes.
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AI-generated art for viral infection of the lungs
Respiratory

Scientists identify a pathway for lung repair after viral infection

Feb. 5, 2024
By Mar de Miguel
A common molecular pathway associated with lung fibrosis may also hold the key to pulmonary vascular repair. A group of scientists at the University of Pennsylvania (Penn) found that when a viral infection damaged these vessels, the injury could be restored by activating the transforming growth factor-β receptor 2 (TGF-βR2) in endothelial cells, which led to cell proliferation.
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Phillips Recall Mask BiPAP CPAP

Philips consent decree with FDA will halt sales of sleep apnea devices

Jan. 30, 2024
By Shani Alexander
Royal Philips NV agreed with the U.S. FDA to the terms of a consent decree focused on its Respironics business, following the recall of millions of its devices over the last few years. Although the details of the decree are being finalized, Philips said it will halt the sales of new continuous positive airway pressure (CPAP) and bilevel positive airway pressure (BiPAP) sleep therapy machines as well as other respiratory care devices in the U.S. until the conditions of the decree are met.
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