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BioWorld - Thursday, February 26, 2026
Home » Topics » Disease categories and therapies » Respiratory

Respiratory
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Woman coughing
Respiratory

Exxel Pharma advances EX-937 for chronic cough

Jan. 29, 2024
Exxel Pharma Inc. is advancing EX-937 for patients suffering from refractory chronic cough. EX-937 works by specifically inhibiting the fatty acid amide hydrolase (FAAH) enzyme, thereby increasing the levels of anandamide, a naturally occurring signaling molecule.
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Respiratory

Prime Medicine receives funding to develop prime editors for cystic fibrosis

Jan. 26, 2024
The Cystic Fibrosis Foundation (CF Foundation) has agreed to provide Prime Medicine Inc. with up to $15 million to support the development of prime editors for the treatment of cystic fibrosis (CF).
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Sanofi campus in Gentilly, France

Inhibrx, Sanofi ratify $2.2B deal for AATD therapy

Jan. 23, 2024
By Randy Osborne
Inhibrx Inc. and Sanofi SA have agreed to a deal worth up to $2.2 billion, whereby the latter’s Aventis Inc. subsidiary will acquire INBRX-101, an optimized, recombinant alpha-1 antitrypsin (AAT) augmentation therapy undergoing a registrational trial for AAT deficiency (AATD), an inherited genetic disorder caused by single nucleotide variants in the SERPINA1 gene.
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Lungs and bronchiole
Respiratory

Targeting VSTM-1 using anti-VSTM-1 agonist MAb reduces COPD pathology in vivo

Jan. 22, 2024
Researchers from Nextcure Inc. have reported the development and preclinical characterization of a novel agonist monoclonal antibody (MAb) against V-set and transmembrane domain containing 1 (VSTM-1).
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Respiratory

Chiesi Farmaceutici presents new TGF-β receptor type-1 inhibitors for IPF

Jan. 19, 2024
Chiesi Farmaceutici SpA has divulged TGF-β receptor type-1 (TGFBR1; ALK5; SKR4; TβR-I) inhibitors reported to be useful for the treatment of idiopathic pulmonary fibrosis (IPF).
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Respiratory

Actelion Pharmaceuticals describes new PDGFR inhibitors for PAH

Jan. 15, 2024
Actelion Pharmaceuticals Ltd. has identified PDGFR inhibitors reported to be useful for the treatment of pulmonary arterial hypertension (PAH).
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IRG respiratory disease management system
Patents

Immersive Reality details respiratory disease management system

Jan. 12, 2024
By Simon Kerton
In what represents the first patenting from Immersive Reality Group LLC, the company’s co-founders describe their Intellighealth system for detecting the early onset of respiratory diseases using artificial intelligence and wearable remote health monitoring technologies.
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Biomarkers

GDF15 is a marker of fibrotic hypersensitivity pneumonitis

Jan. 12, 2024
Hypersensitivity pneumonitis (HP) is an immune-driven interstitial lung disease occurring when susceptible individuals are exposed to antigens.
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Lumitex
Patents

Lumitex Inc. develops device for acute respiratory distress syndrome

Jan. 10, 2024
By Simon Kerton
Lumitex Inc. seeks patent protection for a phototherapeutic apparatus for treating inflammatory conditions, with a particular focus on treating acute respiratory distress syndrome.
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US prices of asthma, COPD inhalers under HELP microscope

Jan. 9, 2024
By Mari Serebrov
When life-saving inhalers sell in Europe at 1.5% to about 8% of their list price in the U.S., they’re bound to attract scrutiny, especially in a time when inequities in prescription drug prices are fueling more and more legislation to reduce U.S. prices.
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