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BioWorld - Saturday, May 16, 2026
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Nephrology

Chinese researchers describe mineralocorticoid receptor antagonists for diabetic nephropathy

Jan. 12, 2023
Jiangsu Chia Tai Tianqing Pharmaceutical Group Co. Ltd. and Medshine Discovery Inc. have identified benzoxazinone derivatives acting as mineralocorticoid receptor (MR) antagonists reported to be useful for the treatment of diabetic nephropathy.
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Infection

Glaxosmithkline divulges new antimalarials

Jan. 12, 2023
Glaxosmithkline Intellectual Property Ltd. has synthesized cytochrome bc1 complex (complex III) (Plasmodium falciparum) inhibitors reported to be useful for the treatment of malaria.
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Neurology/Psychiatric

Celgene patents new S1PR5 modulators for neurodegenerative diseases

Jan. 12, 2023
Celgene Corp. has disclosed sphingosine 1-phosphate receptor 5 (S1PR5; EDG8) modulators reported to be useful for the treatment of Alzheimer's disease and multiple sclerosis.
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Microglia and myelin
Neurology/Psychiatric

Myrtelle and Raaven partner on rAAV vectors for gene therapies for myelin-based disorders

Jan. 12, 2023
Myrtelle Inc. and Raaven Therapeutics AB have partnered on the development of novel recombinant adeno-associated virus (rAAV) vectors to advance gene therapy treatments for diseases of the central nervous system (CNS) in which myelin is affected.
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Cancer

Structural variants activate contiguous oncogenes

Jan. 12, 2023
The alteration of the genome by mutations that...
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Neurology/Psychiatric

Alzecure advances Alzstatin ACD-680 into preclinical development for Alzheimer's

Jan. 12, 2023
Alzecure Pharma AB has selected a candidate...
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Neurology/Psychiatric

Irlab nominates dopamine D1 and D2 receptor agonist IRL-1117 as drug candidate for Parkinson's disease

Jan. 12, 2023
Irlab Therapeutics AB has nominated a drug...
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Microscopic image of acute myeloid leukemia (AML) cells.
Immuno-oncology

CD123-targeted IgM-based bispecific xCD3 antibody, IGM-2537, exhibits potent tumoricidal activity with reduced cytokine release

Jan. 12, 2023
Approximately 20,100 new cases of acute...
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Inflammatory

Novel tryptanthrin derivative ameliorates arthritis in rat model

Jan. 12, 2023
Researchers from Anhui Rubiox-Vision...
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CAR T cell with implanted gene strand
Cancer

CD5-knockout anti-CD5 CAR T-cell product evaluated for relapsed and refractory CD5+ nodal T-cell lymphomas

Jan. 12, 2023
The relative 5-year survival for Non-Hodgkin...
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