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BioWorld - Wednesday, February 18, 2026
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Neurology/Psychiatric

Nanjing Shupeng Lifescience presents new AMPK and PTGS2 inhibitors

Oct. 25, 2022
Compounds acting as AMP-activated protein kinase (AMPK) activators and prostaglandin G/H synthase 2 (PTGS2; COX2) inhibitors have been reported by Nanjing Shupeng Lifescience to be useful for the treatment of pain and inflammatory disorders, among others.
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Infection

Shanghai Jemincare Pharmaceuticals and Jiangxi Jemincare Group identify new antifungal compounds

Oct. 25, 2022
Shanghai Jemincare Pharmaceuticals Co. Ltd. and Jiangxi Jemincare Group Co. Ltd. have patented compounds reported to be useful for the treatment of fungal infections.
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Cancer

Haisco Pharmaceutical Group synthesizes new PRMT5 inhibitors

Oct. 25, 2022
Haisco Pharmaceutical Group Co. Ltd. has described protein arginine N-methyltransferase 5 (PRMT5) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Hainan Sparkle Therapeutics divulges new FGFR2 inhibitors

Oct. 25, 2022
Hainan Sparkle Therapeutics Co. Ltd. has disclosed fibroblast growth factor receptor 2 (FGFR2) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Qilu Regor Therapeutics discloses new CDK2 inhibitors

Oct. 25, 2022
Qilu Regor Therapeutics Inc. has patented cyclin-dependent kinase 2 (CDK2) inhibitors reported to be useful for the treatment of cancer.
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Healthy brain and brain with severe Alzheimer's disease
Neurology/Psychiatric

BACH1 blockade attenuates AD progression in mice

Oct. 25, 2022
Reduced expression of nuclear factor erythroid 2-related factor 2 (Nrf2) is observed in humans and animal models of Alzheimer’s disease (AD), with its activation being a promising therapeutic approach.
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Zebrafish
Neurology/Psychiatric

Gb Sciences' anxiety formulations show promise in preclinical zebrafish models of stress

Oct. 25, 2022
Gb Sciences Inc. has received promising preclinical results in an interim report from a study using its plant-based compounds in preclinical zebrafish models of stress at the National Research Council of Canada (NRC).
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Cancer cells.
Immuno-oncology

Turn's technologies increase ability of T cells to kill cancer in preclinical studies

Oct. 25, 2022
Turn Biotechnologies Inc. has presented interim preclinical data that demonstrates treating T cells with its proprietary technologies can significantly increase their ability to kill cancer.
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Hair and scalp under magnifying glass
Dermatologic

Series A financing at Amplifica supports advancement of candidates for androgenic alopecia

Oct. 25, 2022
Amplifica Holdings Group Inc. has closed a US$11.8 million series A preferred stock financing, the funds from which will be used to advance the development of its proprietary compounds for the treatment of androgenic alopecia in males and females.
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Cancer

99mTc-FGF2 is a novel theragnostic compound for early-stage cancer

Oct. 25, 2022
Recent evidence suggested fibroblast growth factors (FGF) to be involved in epithelium-mesenchymal transition (EMT) and cancer progression.
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