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Neurology/Psychiatric

Series A financing at Teitur Trophics to fund neurodegenerative disease pipeline

March 14, 2023
Teitur Trophics ApS, a spinout from Aarhus University seeded by the Bioinnovation Institute in 2020, has completed a €28 million (US$30.1 million) series A financing. Teitur has developed a platform of first-in-class cyclic peptides with a novel mechanism that preserves neuronal function, and these peptides have the potential to treat a broad range of neurodegenerative diseases.
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Endocrine/Metabolic

Senya Pharmaceuticals discloses TR-β agonists

March 14, 2023
Senya Pharmaceuticals Inc. has patented thyroid hormone receptor beta (TR-β) agonists reported to be useful for the treatment of dyslipidemia, hypercholesterolemia, nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH) and liver disease.
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Metastatic melanoma cells.
Cancer

MAPKAP1 as new therapeutic target in treatment-resistant melanoma

March 14, 2023
The mTORC2 complex plays an important role in the PI3K/AKT/mTOR pathway, allowing activation of AKT and contributing to the development of BRAF-mutated (BRAFm) melanomas and their resistance to treatments. Researchers from Inserm aimed to identify new candidates for targeting the mTORC2 complex in melanoma, with focus on one principal protein of this complex, MAPKAP1 (also known as SIN1).
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