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BioWorld - Thursday, May 14, 2026
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Infection

Researchers describe new qcrB inhibitors for tuberculosis

Dec. 2, 2022
Researchers at St. Louis University, Washington University in St. Louis, and Fimbrion Therapeutics Inc. have identified ubiquinol-cytochrome C reductase cytochrome b subunit (qcrB) (Mycobacterium tuberculosis) inhibitors reported to be useful for the treatment of tuberculosis.
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Brain clay model
Neurology/Psychiatric

Neuroanatomy analysis of new mouse models of autism

Dec. 2, 2022
Researchers from The Hospital for Sick Children have created mouse models related to autism. Nine novel models related to autism were produced in C57BL/6NCrl (B6N) mice using loss-of-function mouse lines with knockout of genes Katnal2, L2hgdh, Nexmif, Otc, Pah, Rab39b, Ranbp17, Upf3b and Ypel2.
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Brain waves
Neurology/Psychiatric

US researchers divulge new 5-HT2A receptor agonists

Dec. 2, 2022
Researchers at Medical College of Wisconsin, University of California Oakland and University...
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Immuno-oncology

Pyxis provides update on ADC and immunotherapy candidates for solid tumors

Dec. 2, 2022
Pyxis Oncology Inc. has received FDA clearance for its two IND applications to initiate phase I trials...
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Neurology/Psychiatric

GW Research patents new cannabidiol-C4 derivatives for epilepsy

Dec. 2, 2022
GW Research Ltd. has disclosed cannabidiol-C4 (CBD-C4) derivatives reported to be useful for...
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Hepatitis B virus
Infection

Bluejay set to advance BJT-778 for chronic hepatitis B and chronic hepatitis D

Dec. 2, 2022
Bluejay Therapeutics Inc. has received approval from the New Zealand Medicines and Medical...
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Immune checkpoint inhibitors illustration of PD-1, CTLA-4 and PD-L1.
Immuno-oncology

Hillstream announces Knob Quatrabodies program targeting PD-1

Dec. 2, 2022
Hillstream Biopharma Inc. has announced the development of proprietary targeted biologics...
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Cancer

Surviving colon cancer cells activate P2X4-dependent mTOR pathway

Dec. 2, 2022
Goethe University Frankfurt researchers and their collaborators conducted a study to examine...
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Drug capsule spilling onto brain
Neurology/Psychiatric

Ventus Therapeutics nominates brain-penetrant NLRP3 inhibitor as second development candidate

Dec. 2, 2022
Ventus Therapeutics Inc. is advancing its novel NLRP3 inhibitor programs and announced...
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Close-up of eye with digital focus
Ocular

Preclinical data on Valitor's anti-VEGF therapy support twice-yearly dosing in wet AMD

Dec. 2, 2022
Valitor Inc. has disclosed its next-generation anti-VEGF therapy, VLTR-557, for wet age-related...
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