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BioWorld - Wednesday, April 22, 2026
Home » Topics » Drug design, drug delivery and technologies, BioWorld Science

Drug design, drug delivery and technologies, BioWorld Science
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Illustration of cobra in front of protein structures
Substance use & poisoning

An antidote to cobra venom designed with AI

Jan. 21, 2025
By Mar de Miguel
Following Nobel Prize-winning chemist David Baker’s recipe for cooking an antidote to cobra venom using artificial intelligence (AI) could be faster and more effective than currently available methods. The ingredients and steps can be found in a new study published by the University of Washington (UW) scientist in collaboration with the Technical University of Denmark. They are ready for the next steps in preclinical trials.
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Scanning electron micrograph of M. tuberculosis
Respiratory

In monkeys, enhanced TB vaccine dissolves after inducing protection

Jan. 14, 2025
By Mar de Miguel
An experimental tuberculosis (TB) vaccine with a dual mission – self-destruction after inducing immunity – improved the design of the Bacillus Calmette-Guérin (BCG) immunotherapy, a vaccine also used against cancer. Scientists at the University of Pittsburgh engineered this strain with a double break, which is effective and safer after an intravenous administration, according to their results in nonhuman primates and mice.
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Blood samples in lab
Drug design, drug delivery & technologies

Proteomics study explores how protein changes influence disease

Jan. 13, 2025
By Nuala Moran
Fourteen global pharma companies are getting together to conduct the largest proteomics study to date, analyzing 600,000 blood samples held in the UK Biobank to assess the levels of 5,400 different proteins.
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Drug capsule spilling onto brain
Neurology/psychiatric

Tenvie Therapeutics launches with focus on neurological diseases

Jan. 9, 2025
The company is advancing a pipeline of therapeutics, including programs acquired from Denali Therapeutics Inc., focused on treating neurological, cardiometabolic and ophthalmic diseases.
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Drug R&D concept image.
Cancer

Rakovina advances synthesis of PARP1-selective inhibitors

Jan. 7, 2025
Rakovina Therapeutics Inc. has announced the successful synthesis of novel small-molecule drug candidates designed under the company’s artificial intelligence (AI) platform collaboration.
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Female researcher wearing mask and safety glasses holding dropper
Drug design, drug delivery & technologies

Institut Pasteur Korea and POSTECH institutes to collaborate on infectious disease research

Jan. 3, 2025
Institut Pasteur Korea has signed a memorandum of understanding (MOU) with four Pohang University of Science and Technology (POSTECH)-affiliated research institutes with the aim of pursuing joint research on mRNA vaccine and treatment development.
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Nanoparticle illustration
Drug design, drug delivery & technologies

Altamira Therapeutics achieves nanoparticle-based delivery of circular mRNA

Jan. 2, 2025
Altamira Therapeutics Ltd.’s nanoparticle-based delivery platform has been successfully tested for circular mRNA.
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Drug design, drug delivery & technologies

Atavistik Bio collaborates with Pfizer to discover allosteric therapeutics

Jan. 2, 2025
Atavistik Bio Inc. has entered into a research collaboration with Pfizer Inc. to accelerate the discovery of novel precision allosteric therapeutics for unmet medical needs. Under the collaboration, Atavistik Bio will leverage its proprietary AMPS platform to identify novel allosteric binders against two undisclosed targets selected by Pfizer.
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Illustration of a road with three destination markers
Drug design, drug delivery & technologies

Second development milestone reached in Peptidream/J&J collaboration

Dec. 27, 2024
The milestone is for the identification of candidates meeting the predefined lead compound criteria, and follows the initial milestone achieved in December 2023.
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Cancer

Engineered yeast probiotics as carrier for GI tumor therapy

Dec. 24, 2024
Engineered probiotics, mainly bacterial probiotics, are an emerging platform for in situ delivery of therapeutics, including anticancer therapies, to the gut. Writing in Cell Chemical Biology, researchers from Washington University School of Medicine and collaborators present a novel yeast-based therapeutic oral platform to deliver next-generation immune checkpoint inhibitor proteins directly to gastrointestinal tumors.
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