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BioWorld - Tuesday, April 14, 2026
Home » epilepsy

Articles Tagged with ''epilepsy''

Epileptic brain and abnormal EEG wave discharges
Neurology/Psychiatric

AEG-1 regulates granule cell dispersion, seizure development in model of temporal lobe epilepsy

May 24, 2023
Researchers from Kyungpook National University presented data from a study that aimed to investigate the endogenous mechanisms involved in granule cell dispersion (GCD) and its role in epileptic seizures in temporal lobe epilepsy (TLE).
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Brain and encephalography

JCR partners with Angelini on biologic therapies for epilepsy

May 16, 2023
By Zhang Mengying
Angelini Pharma SpA and JCR Pharmaceuticals Co. Ltd. signed an exclusive worldwide agreement for the development and commercialization of biologic therapies for epilepsy based on the J-Brain Cargo technology.
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Brain and encephalography

JCR partners with Angelini on biologic therapies for epilepsy

May 15, 2023
By Zhang Mengying
Angelini Pharma SpA and JCR Pharmaceuticals Co. Ltd. signed an exclusive worldwide agreement for the development and commercialization of biologic therapies for epilepsy based on the J-Brain Cargo technology.
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Brain and encephalography
Neurology/Psychiatric

Angelini and JCR collaborate to develop and commercialize novel biologic therapies for epilepsy

May 12, 2023
Angelini Pharma SpA and JCR Pharmaceuticals Co. Ltd. have entered into an exclusive global development and commercialization agreement for the development of novel biologic therapies that applies J-Brain Cargo blood-brain barrier penetrating technology for the treatment of epilepsy, applying undisclosed effectors.
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Neurology/Psychiatric

Xenon Pharmaceuticals divulges new Nav1.1 activators for epilepsy

April 19, 2023
Xenon Pharmaceuticals Inc. has synthesized pyridinyl derivatives acting as sodium channel protein type 1 subunit α (SCN1A; Nav1.1) activators reported to be useful for the treatment of epilepsy.
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Neurology/Psychiatric

Hangzhou Healzen Therapeutics presents new KCNQ2/3 potassium channel activators

March 21, 2023
Hangzhou Healzen Therapeutics Co. Ltd. has divulged potassium voltage-gated channel subfamily KQT member 2/3 (KCNQ2/3) activators reported to be useful for the treatment of epilepsy, among others.
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Brain and encephalography
Neurology/Psychiatric

BHV-7000 demonstrates efficacy and safety in maximal electroshock seizure rat model

March 20, 2023
Researchers from Biohaven Pharmaceutical Holding Co. Ltd. presented preclinical data for...
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Equilibre’s anti-inflammatory sees phase II success in epilepsy

Jan. 30, 2023
By Lee Landenberger
Equilibre Biopharmaceuticals Corp. has positive top-line data from the phase II study of its lead asset, EQU-001, an anti-inflammatory adjunctive therapy for treating focal seizures for adults with epilepsy.
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Cross section of brain
Biomarkers

Multi-omic profiling unveils mutated genes in malformations of cortical development

Jan. 17, 2023
Malformations of cortical development (MCD) are a group of neurodevelopmental disorders characterized by malformation of cortical structures, which often lead to epilepsy, and include cortical dysplasia (FCD), hemimegalencephaly (HME) and tuberous sclerosis complex (TSC).
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Brain and encephalography
Neurology/Psychiatric

Researchers design novel p38γ-targeting gene therapy to treat epilepsy

Jan. 9, 2023
It has been shown that site-specific phosphorylation of tau at threonine 205 (T205) by the kinase p38γ disengages tau from toxic pathways, thus acting as a neuroprotective function in Alzheimer’s disease. Researchers in Australia have designed a novel AAV-based gene therapy approach targeting p38γ, DBA/2.p38γCA, in murine models of epilepsy in which tau is known to play a neurotoxic effect.
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