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BioWorld - Sunday, March 29, 2026
Home » Topics » Clinical

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Silhouettes

Researchers ID new method to monitor schizophrenia drug in blood

March 4, 2021
By David Ho
HONG KONG – Researchers at Ben-Gurion University of the Negev (BGU) in Israel have developed a way to instantly monitor blood levels of the antipsychotic drug clozapine. BGU’s solution is based on an electrochemical microsensor developed by Hadar Ben-Yoav from BGU’s Department of Biomedical Engineering and Ilse Katz Institute for Nanoscale Science and Technology.
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Cuba mask and syringe

Cuba’s Soberana 02 SARS-CoV-2 vaccine candidate moves to phase III trials

March 4, 2021
By Sergio Held
CAJICA, Colombia – Cuba’s Center for the State Control of Drugs, Equipment and Medical Devices gave the green light March 3 for phase III trials of a domestically developed COVID-19 vaccine candidate, even though very little peer-reviewed information has been published about it.
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In the clinic for March 4, 2021

March 4, 2021
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Abivax, Allarity, Apollomics, Cyclo, Dicerna, Diamyd, Dnatrix, Galapagos, Landos, Lilly, Mallinckrodt, Provention, Ridgeback, Roche, TFF, VBL, Ysopia.
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In the clinic for March 3, 2021

March 3, 2021
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Amgen, Arena, Azura, Bharat, Biomarin, Forendo, GSK, Incyte, Karolinska, Lilly, Longeveron, Maker, Morphosys, Ocugen, Prometheus, Reveragen, Santhera, Spectrum, Vir.
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Ascletis joins Madrigal and Viking in global race for THR-β agonist for NASH

March 2, 2021
By Elise Mak
Liver disease specialist Ascletis Pharma Inc. said its nonalcoholic steatohepatitis (NASH)-focused subsidiary, Gannex Pharma Co. Ltd., will start global development of its oral THR-β agonist, ASC-41, after it obtained an IND approval from the FDA based on positive phase I data generated in China.
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Silhouettes

Neurocrine schizophrenia thesis intact post-Interact? Opinions differ on phase II data

March 2, 2021
By Randy Osborne
San Diego-based Neurocrine Biosciences Inc.’s good-and-bad top-line phase II data with d-amino acid oxidase inhibitor luvadaxistat, also known NBI-1065844 and TAK-831, in schizophrenia likely came as little surprise to many, given earlier experience in the general pathway.
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In the clinic for March 2, 2021

March 2, 2021
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Aileron, Avadel, Biomx, Cerecor, Clearside, Gemoab, Highlight, Hoth, Inovio, Kymera, Eurocrine, Neurosense, NGM, Orbus, Pipeline, Scynexis, Seres.
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In the clinic for March 1, 2021

March 1, 2021
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Accure, Algernon, Annexon, Aslan, Bioinvent, Innovent, Morphic, Ocular, Samsung Bioepis, Santhera, Satsuma, Takis, Transgene, VBL.
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Illustration of digital syringe

Nference, Mayo Clinic study ties prior vaccinations to COVID-19 defense

Feb. 26, 2021
By Meg Bryant
A new study by Mayo Clinic and Nference Inc. researchers suggests that prior childhood and adult vaccinations for illnesses such as polio, measles and flu may provide protection against COVID-19 infection. The study, which analyzed patient data using Nference artificial intelligence (AI) software, underscores the critical role immunizations play in curbing the spread of diseases and preventing future pandemics. “What we discovered represents compelling evidence that vaccinations are a critical element in prevention of disease, even diseases one doesn’t anticipate,” said Venky Soundararajan, co-founder and chief scientific officer of the Cambridge, Mass.-based company.
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Lack of clinical trial diversity could have consequences

Feb. 26, 2021
By Mari Serebrov
Drug and device companies dragging their feet on diversifying late-stage clinical trials could conceivably get a wake-up call in court or in FDA approval delays.
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