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BioWorld - Monday, January 19, 2026
Home » Topics » Disease categories and therapies » Cancer

Cancer
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RLY-2608, novel mutant and isoform selective inhibitor of PI3Kalpha

Oct. 15, 2021

New TGF-beta receptor type-1 inhibitors described by Adlai Nortye

Oct. 15, 2021

Wigen Biomedicine Technology patents G12C mutant GTPase KRAS inhibitors

Oct. 15, 2021

New EGFR inhibitors identified at Qilu Pharmaceutical

Oct. 15, 2021

CT-7439: a potential first-in-class oral cyclin K glue degrader

Oct. 15, 2021
Coins and charts

Tentarix closes $50M series A round to probe ‘combinatorial space’ for multifunctional drugs

Oct. 14, 2021
By Cormac Sheridan
Tentarix Biotherapeutics LP broke cover with $50 million in series A funding to take forward an industrialized flow cytometry platform that enables it to screen rapidly for multifunctional antibody-based drugs.
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Too early to say ‘WEE1,’ but strides made in validating approach to cancer

Oct. 14, 2021
By Randy Osborne
Recent news that The University of Texas MD Anderson Cancer Center is teaming up with Schrödinger Inc. to work on the latter’s WEE1 inhibitor – along with data disclosed at the 2021 meeting of the European Society for Medical Oncology (ESMO) – shone a light on the gatekeeper checkpoint kinase, which a number of players are busy exploring, though nothing in the class has been approved so far.
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Abalos adds $38M in series A extension to take virotherapy into the clinic

Oct. 14, 2021
By Cormac Sheridan
DUBLIN – Abalos Therapeutics GmbH raised €32.5 million (US$37.6 million) in a series A extension, taking the total raise to €43 million, enough to enable the company to generate clinical proof-of-concept data with its lead viral immunotherapy for cancer.
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Lung cancer illustration

Overcoming EGFR-targeted TKI lung cancer resistance

Oct. 14, 2021
By John Fox
A novel pharmacologically targetable metabolic mechanism driving resistance to epidermal growth factor receptor (EGFR)-targeting tyrosine kinase inhibitors (TKIs) has been identified in preclinical models of lung cancer in a Chinese study led by scientists at Shanghai Jiao Tong University School of Medicine.
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Ikena Oncology targets TEAD transcription in cancer with IK-930

Oct. 14, 2021
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