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BioWorld - Friday, March 6, 2026
Home » Topics » Immune, Medical technology

Immune, Medical technology
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U.S. flag on columned building

Stopgaps help some survive, but over time, NIH funding is unique

Aug. 22, 2025
By Anette Breindl
No Comments
On Thursday, the Supreme Court handed the Trump administration another significant victory in its attempts to defund NIH-sponsored research. In a 5-4 decision, the justices paused the June 16 order of U.S. District Judge William Young to restore funding for hundreds of canceled NIH research grants focusing on gender and diversity, equity and inclusion (DEI). The funding had first been cut through a series of executive orders shortly after President Donald Trump resumed power in January.
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Results of lithium orotate vs. lithium carbonate on amyloid-β and tau
Neurology/psychiatric

Lithium could change Alzheimer's care, but not all forms work

Aug. 14, 2025
By Mar de Miguel
No Comments
The difference between the origin of Alzheimer's disease (AD) and its symptoms is an obstacle to finding effective treatments. Scientists focused on amyloid-β (Aβ) plaques and tau aggregates to slow neurodegeneration and cognitive decline. Without identifying what causes AD, approved treatments do not provide much benefit.
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Genome sequence map
Immune

UK’s DecodeME uncovers genetic link for chronic fatigue

Aug. 12, 2025
By Nuala Moran
No Comments
The largest genome-wide association study to date of myalgic encephalomyelitis/chronic fatigue syndrome has identified eight genetic loci that are significantly associated with the chronic debilitating condition. Onset of ME/CFS often is traced back to an infection and four of the loci involve genes that are expressed in response to viral or bacterial infections.
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HKEX exterior

34 mainland China biotechs file for Hong Kong IPO in H1 2025

July 24, 2025
By Marian (YoonJee) Chu
No Comments
Thirty-six biotechnology, pharmaceutical and medical device companies sought a capital raise on the Hong Kong Stock Exchange in the first half (H1) of 2025, a review by BioWorld found. Of those, 34 companies were from mainland China.
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HKEX exterior

34 mainland China biotechs file for Hong Kong IPO in H1 2025

July 24, 2025
By Marian (YoonJee) Chu
No Comments
Thirty-six biotechnology, pharmaceutical and medical device companies sought a capital raise on the Hong Kong Stock Exchange in the first half (H1) of 2025, a review by BioWorld found. Of those, 34 companies were from mainland China.
Read More
HKEX exterior

34 mainland China biotechs file for Hong Kong IPO in H1 2025

July 18, 2025
By Marian (YoonJee) Chu
No Comments
Thirty-six biotechnology, pharmaceutical and medical device companies sought a capital raise on the Hong Kong Stock Exchange in the first half (H1) of 2025, a review by BioWorld found. Of those, 34 companies were from mainland China.
Read More
3D rendering of a molecular glue mediating the interaction between two proteins
Drug design, drug

With surface mimicry, molecular glues shed hairpin need

July 15, 2025
By Anette Breindl
No Comments
Degradation is a therapeutic strategy that could offer possibilities to get at currently undruggable target proteins. In targeted degradation, compounds induce interactions between a target protein and a protein that can tag the target for degradation. In principle, there are several pathways that could be used for such tagging; the most attention has gone to ubiquitin ligases, in particular cereblon, a protein that is part of a ubiquitin ligase complex and the target of several approved drugs.
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3D rendering of a molecular glue mediating the interaction between two proteins
Drug design, drug

With surface mimicry, molecular glues shed hairpin need

July 10, 2025
By Anette Breindl
No Comments
Degradation is a therapeutic strategy that could offer possibilities to get at currently undruggable target proteins. In targeted degradation, compounds induce interactions between a target protein and a protein that can tag the target for degradation. In principle, there are several pathways that could be used for such tagging; the most attention has gone to ubiquitin ligases, in particular cereblon, a protein that is part of a ubiquitin ligase complex and the target of several approved drugs.
Read More
Drug vials

Industry could feel fallout of Pfizer vaccine scrutiny

July 3, 2025
By Mari Serebrov
No Comments
In subpoenaing a former Pfizer Inc. official to appear before the U.S. House Judiciary Committee July 22, Judiciary Chair Jim Jordan, R-Ohio, signaled legislative steps Congress may take in response to allegations that Pfizer slow-walked its COVID-19 vaccine development in 2020 so the trial results wouldn’t have to be disclosed until after the presidential election.
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3D rendering of CAR T therapy in cell
Neurology/psychiatric

EAN 2025: CAR T cells take on neurological disorders

June 25, 2025
By Anette Breindl
No Comments
At the 11th Congress of the European Academy of Neurology, which was held in Helsinki June 21 to June 24, researchers presented new data on using CAR T cells in autoimmune neurological conditions.
Read More
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