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BioWorld - Thursday, June 19, 2025
Home » Topics » Disease categories and therapies » Infection

Infection
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JAMA OpEd

Too much at stake for dismissed ACIP members to go quietly

June 18, 2025
By Mari Serebrov
No Comments
The 17 members abruptly terminated June 9 from the U.S. CDC’s Advisory Committee for Immunization Practices are not going gently into the night. Instead, they’re raging against what could be the dying of the light.
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Jyong’s $20M US IPO to help refile NDA of urological botanic drug

June 18, 2025
By Marian (YoonJee) Chu
No Comments
Jyong Biotech Ltd. raised $20 million from its Nasdaq debut June 17 to advance a pipeline of botanical drugs targeting male urinary disorders. The New Taipei City, Taiwan-headquartered company’s shares began trading under the ticker MENS, and closed at $10.11 apiece at the bell, up 34.80% from its listing price of $7.50 per share. Shares had kicked up to $15 at opening, reaching double its offering price.
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Infection

Assembly Biosciences describes new azetidine compounds for HSV infections

June 18, 2025

Assembly Biosciences Inc. has identified azetidine compounds reported to be useful for the treatment of herpes simplex virus (HSV) infections. 


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JAMA OpEd

Too much at stake for dismissed ACIP members to go quietly

June 17, 2025
By Mari Serebrov
No Comments
The 17 members abruptly terminated June 9 from the U.S. CDC’s Advisory Committee for Immunization Practices (ACIP) are not going gently into the night. Instead, they’re raging against what could be the dying of the light. The 17 raised their collective voices in a June 16 JAMA opinion piece to decry what’s at stake with Health and Human Services Secretary Robert Kennedy’s efforts, in his words, to “reestablish public confidence in vaccine science” by cleansing ACIP of what he claimed were conflicts due to members’ financial ties to industry.
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DNA strand over digital lock and circuit background

BIO 2025: Building biosecurity through public-private partnership

June 16, 2025
By Karen Carey
No Comments
The COVID-19 pandemic sent the world into a tailspin, raising ongoing concerns about biosecurity, a subject that encompassed the better part of the morning June 16, the first day of the Biotechnology Innovation Organization’s annual conference in Boston.
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Colorized transmission electron micrograph of SARS-CoV-2 (UK B.1.1.7 variant).
Infection

Researchers develop NSP8-derived peptides successfully targeting SARS-CoV-2 replication machinery

June 16, 2025
No Comments
Researchers from the Institute for Basic Science of Korea and collaborating institutions have designed a new class of peptide-based inhibitors targeting a crucial interface within the SARS-CoV-2 replication complex, offering a potential new avenue for antiviral therapy.
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New ACIP members to review data for current vaccine schedules

June 12, 2025
By Mari Serebrov
No Comments
And then there were eight. That is, eight members of the U.S. CDC’s Advisory Committee for Immunization Practices (ACIP).Two days after dismissing the 17 members of the committee, Health and Human Services Secretary Robert Kennedy named eight new members to the panel. Eight is the minimum required for a quorum, which will be necessary for the June 25-27 ACIP meeting.
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Stock merger illustration

Biontech’s $1.25B Curevac buyout removes mRNA lawsuit uncertainty

June 12, 2025
By Karen Carey
No Comments
Three years after litigation started over technology used in an mRNA vaccine for COVID-19, Biontech SE is acquiring its adversary, Curevac NV, through an all-stock transaction valued at about $1.25 billion. The amount is lower than the $3 billion in backpay Curevac could win through the lawsuit if a low mid-single-digit royalty were awarded, Evercore ISI analysts Jon Miller and Umer Raffat said. But the legal uncertainty has weighed heavily on the company, which shed 30% of its workforce last July and sold off rights to two of its infectious disease vaccines.
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Infection

European researchers divulge new ECF inhibitors

June 12, 2025
Scientists at Helmholtz Zentrum für Infektionsforschung GmbH, Rijksuniversiteit Groningen and Université de Lausanne have synthesized energy-coupling factor (ECF) transporter (bacterial) inhibitors reported to be useful for the treatment of enterococcal and streptococcal infections.
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Illustration of human papillomavirus infection
Cancer

Gates Foundation grant supports Octant’s new program in HPV-related cancers

June 12, 2025
No Comments
Octant Inc. has received a $4.9 million grant from the Gates Foundation to support a new therapeutics program focused on human papillomavirus (HPV)-related cancers. The initiative will develop affordable, broad-spectrum, small-molecule antiviral drugs designed to disrupt the interaction between hundreds of variants of the HPV E6 protein and the tumor suppressor protein p53.
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