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BioWorld - Monday, March 23, 2026
Home » Topics » Disease categories and therapies » Infection

Infection
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After judge’s injunction, will ACIP disband?

March 20, 2026
No Comments
A member of the CDC’s Advisory Committee on Immunization Practices (ACIP), physician and biochemist Robert Malone, who a judge earlier this week suggested lacked vaccine-related experience, wrote March 19 on X that the committee “has been disbanded.” Nearly six hours later, he followed up, saying it was a “miscommunication.”
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Infection

Sichuan Kelun Pharmaceutical synthesizes CYP51 inhibitors

March 20, 2026
Sichuan Kelun Pharmaceutical Co. Ltd. has discovered new lanosterol 14α-demethylase (CYP51) inhibitors reported to be useful for the treatment of Candidal infection and aspergillosis.
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Researcher in lab with Petri dishes.
Infection

PK/PD analysis of KSP-1007 plus meropenem supports combination treatment

March 20, 2026
No Comments
KSP-1007 is a new bicyclic boronate-based broad-spectrum β-lactamase inhibitor that, in combination with meropenem, is under development for the treatment of infections caused by carbapenem-resistant gram-negative bacteria that produce serine- and metallo-type carbapenemases.
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Gavel, stethoscope, vial and syringe

Judge’s order shuts down new vaccine schedule, ACIP itself

March 17, 2026
By Mari Serebrov
No Comments
In one fell swoop March 16, a U.S. federal judge stayed the CDC’s January memo revising the childhood vaccine schedule and the Advisory Committee on Immunization Practices (ACIP) as reconstituted by Health and Human Services Secretary Robert Kennedy, along with everything that committee has done since early June.
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Virus and drug illustration
Infection

Aptar and Covirix Medical collaborate on inhaled antivirals

March 13, 2026
No Comments
Aptar Pharma, part of Aptargroup Inc., has established a technical collaboration with Covirix Medical Pty Ltd. under a letter of intent to develop inhaled antiviral treatments.
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Drug capsules in petri dish

Latest benchmark shows 35% decline in antibiotics pipeline in past 5 years

March 10, 2026
By Nuala Moran
No Comments
Twelve years on from the World Health Organization formally raising the alarm, antimicrobial resistance continues to grow, and despite numerous public and private incentives and initiatives, the pipeline of antibiotics in development is thinner than ever.
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HIV/AIDS

Shionogi patents new agents for HIV-1 infection

March 10, 2026
Shionogi & Co. Ltd. has disclosed heterocyclic derivatives characterized as reverse transcriptase/ribonuclease H (HIV-1) inhibitors for potential use in the treatment of HIV infection.
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Illustration of liver infected by hepatitis E
Infection

Atea Pharma presents data on compounds for hepatitis E

March 10, 2026
No Comments
Atea Pharmaceuticals Inc. recently presented preclinical data on two of its compounds, AT-2490 and AT-587, which have shown promising antiviral potential for treating hepatitis E virus infection.
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Vaccine vials and syringe
Infection

Replication-incompetent HAdV-55 vaccine provides in vivo protection against pathogenic adenoviruses

March 10, 2026
No Comments
Aiming to develop a vaccine candidate against human adenovirus-55 (HAdV-55) infections, researchers from the First Affiliated Hospital of Guangzhou Medical University (China) and collaborators have generated a replication-incompetent rAd55-5E4.
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Transmission electron micrograph of HIV-1 virus particles
HIV/AIDS

KLF16 as potential target for HIV management

March 5, 2026
No Comments
HIV-1 persistence in latent reservoirs of T lymphoid and myeloid origin is a major barrier for the cure of the disease, with complex and multifactorial mechanisms behind HIV-1 latency; thus, investigating these mechanisms is key for future targeted HIV therapies.
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