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BioWorld - Friday, December 26, 2025
Home » Topics » Disease categories and therapies » Infection

Infection
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Mycobacterium tuberculosis
Infection

MBX-4888A shows beneficial additive effect in subacute and chronic TB models

Oct. 17, 2024
Investigators from Microbiotix Inc. have published preclinical data for the novel spectinamide, MBX-4888A (Lee-1810), being developed for the treatment of tuberculosis (TB).
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FDA pauses Novavax’s flu and COVID-19 combo vaccines

Oct. 16, 2024
By Jennifer Boggs
Shares of Novavax Inc. (NASDAQ:NVAX) dropped nearly 20% Oct. 16 to close at $10.15 after the company reported a serious adverse event had prompted a U.S. FDA clinical hold for its COVID-19-influenza combination and standalone flu vaccine candidates.
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SK Bioscience to invest $3M in US vaccine maker Fina Biosolutions

Oct. 15, 2024
By Marian (YoonJee) Chu
SK Bioscience Co. Ltd., of Seongnam-si, South Korea, said Oct. 8 that it will acquire a $3 million stake in Fina Biosolutions LLC to become the first and sole strategic investor of the Rockville, Md.-based vaccine specialist. For SK Bioscience, the investment is slated to boost its vaccine R&D capabilities, the company said, which currently includes manufacturing of pneumococcal and typhoid conjugate vaccines.
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Illustration of liver infection
Infection

Repurposing ifenprodil for the treatment of hepatitis E virus infection

Oct. 15, 2024
Currently, there are no specific antiviral drugs available for treating hepatitis E virus (HEV) infection, which represents a global health burden, causing acute viral hepatitis with varying clinical outcomes.
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Clostridium difficile bacteria
Infection

A novel mRNA-LNP vaccine facilitates Clostridioides difficile control

Oct. 11, 2024
By Coia Dulsat
Clostridioides difficile is traditionally isolated from healthcare facilities' inpatients, but it is increasingly being identified in people who have not recently been hospitalized and is more and more found in community settings. Investigators from Perelman School of Medicine at University of Pennsylvania developed an mRNA-LNP vaccine with promising results in preventing and controlling C. difficile infection.
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Clostridium difficile bacteria

A novel mRNA-LNP vaccine facilitates Clostridioides difficile control

Oct. 11, 2024
By Coia Dulsat
Clostridioides difficile has been traditionally isolated from health care facilities' inpatients, but it is increasingly being identified in people who have not recently been hospitalized and is more and more found in community settings. Investigators from Perelman School of Medicine at University of Pennsylvania have developed an mRNA-LNP vaccine with promising results in preventing and controlling C. difficile infection.
Read More
Cancer cells under magnifying glass
Cancer

MMV-1645152 blocks the KSHV lytic lifecycle

Oct. 10, 2024
Researchers from Rhodes University and collaborators identified MMV-1645152 after screening the Medicines for Malaria Venture (MMV) pandemic response box for non-cytotoxic inhibitors of Kaposi's sarcoma-associated herpesvirus (KSHV) replication.
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Clostridium difficile bacteria
Infection

A novel mRNA-LNP vaccine facilitates Clostridioides difficile control

Oct. 10, 2024
By Coia Dulsat
Clostridioides difficile has been traditionally isolated from healthcare facilities' inpatients, but it is increasingly being identified in people who have not recently been hospitalized and is more and more found in community settings. Investigators from Perelman School of Medicine at University of Pennsylvania have developed an mRNA-LNP vaccine with promising results in preventing and controlling C. difficile infection.
Read More

SK Bioscience to invest $3M in US vaccine maker Fina Biosolutions

Oct. 9, 2024
By Marian (YoonJee) Chu
SK Bioscience Co. Ltd., of Seongnam-si, South Korea, said Oct. 8 that it will acquire a $3 million stake in Fina Biosolutions LLC to become the first and sole strategic investor of the Rockville, Md.-based vaccine specialist. For SK Bioscience, the investment is slated to boost its vaccine R&D capabilities, the company said, which currently includes manufacturing of pneumococcal and typhoid conjugate vaccines.
Read More
Microscope with beakers and flasks
Infection

Tonix and X-Chem collaborate to accelerate broad-spectrum antiviral development

Oct. 9, 2024
Tonix Pharmaceuticals Holding Corp. has entered into an artificial Intelligence and machine learning research collaboration with X-Chem Inc. to accelerate development of Tonix’s oral broad-spectrum antivirals for medical countermeasures.
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