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BioWorld - Friday, April 10, 2026
Home » Topics » Disease categories and therapies » Infection

Infection
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Clostridium difficile bacteria
Infection

A novel mRNA-LNP vaccine facilitates Clostridioides difficile control

Oct. 11, 2024
By Coia Dulsat
Clostridioides difficile is traditionally isolated from healthcare facilities' inpatients, but it is increasingly being identified in people who have not recently been hospitalized and is more and more found in community settings. Investigators from Perelman School of Medicine at University of Pennsylvania developed an mRNA-LNP vaccine with promising results in preventing and controlling C. difficile infection.
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Clostridium difficile bacteria

A novel mRNA-LNP vaccine facilitates Clostridioides difficile control

Oct. 11, 2024
By Coia Dulsat
Clostridioides difficile has been traditionally isolated from health care facilities' inpatients, but it is increasingly being identified in people who have not recently been hospitalized and is more and more found in community settings. Investigators from Perelman School of Medicine at University of Pennsylvania have developed an mRNA-LNP vaccine with promising results in preventing and controlling C. difficile infection.
Read More
Cancer cells under magnifying glass
Cancer

MMV-1645152 blocks the KSHV lytic lifecycle

Oct. 10, 2024
Researchers from Rhodes University and collaborators identified MMV-1645152 after screening the Medicines for Malaria Venture (MMV) pandemic response box for non-cytotoxic inhibitors of Kaposi's sarcoma-associated herpesvirus (KSHV) replication.
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Clostridium difficile bacteria
Infection

A novel mRNA-LNP vaccine facilitates Clostridioides difficile control

Oct. 10, 2024
By Coia Dulsat
Clostridioides difficile has been traditionally isolated from healthcare facilities' inpatients, but it is increasingly being identified in people who have not recently been hospitalized and is more and more found in community settings. Investigators from Perelman School of Medicine at University of Pennsylvania have developed an mRNA-LNP vaccine with promising results in preventing and controlling C. difficile infection.
Read More

SK Bioscience to invest $3M in US vaccine maker Fina Biosolutions

Oct. 9, 2024
By Marian (YoonJee) Chu
SK Bioscience Co. Ltd., of Seongnam-si, South Korea, said Oct. 8 that it will acquire a $3 million stake in Fina Biosolutions LLC to become the first and sole strategic investor of the Rockville, Md.-based vaccine specialist. For SK Bioscience, the investment is slated to boost its vaccine R&D capabilities, the company said, which currently includes manufacturing of pneumococcal and typhoid conjugate vaccines.
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Microscope with beakers and flasks
Infection

Tonix and X-Chem collaborate to accelerate broad-spectrum antiviral development

Oct. 9, 2024
Tonix Pharmaceuticals Holding Corp. has entered into an artificial Intelligence and machine learning research collaboration with X-Chem Inc. to accelerate development of Tonix’s oral broad-spectrum antivirals for medical countermeasures.
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Colorized scanning electron micrograph of mpox virus (red) on the surface of infected VERO E6 cells (green).
Infection

MPXV-1103, a quadrivalent mpox mRNA vaccine, exhibits safety and efficacy

Oct. 9, 2024
Researchers from University of Science and Technology of China (USTC) published data for a novel multivalent mRNA mpox vaccine candidate, MPXV-1103.
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Disintegrating coronavirus
Infection

PKI-179 and MTI-31 identified as potent anti-coronavirus compounds

Oct. 8, 2024
The COVID-19 pandemic pushed the urgency for effective antiviral drugs against coronaviruses. Researchers from Europe conducted machine learning and in vitro validation experiments for the identification of potential antiviral drugs effective against coronaviruses.
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El Camino Health FloPatch

Flosonics’ Flopatch helps reduce sepsis mortality from 30% to 5%

Oct. 7, 2024
By Annette Boyle
Implementation of Flosonics Medical Inc.’s Flopatch reduced sepsis-associated mortality more than 80% in a California public hospital, a case study showed. A wearable Doppler ultrasound device, Flopatch continuously assesses blood flow to guide fluid delivery and resuscitation in critically ill patients.
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Bacteria in petri dishes
Infection

MEK1/2 inhibitor shows antibacterial and anti-inflammatory effects

Oct. 7, 2024
It was hypothesized that the MEK1/2 inhibitor ATR-002 could reduce inflammation and clear Staphylococcus aureus infection during cystic fibrosis, thus potentially showing a dual effect.
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