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BioWorld - Wednesday, April 15, 2026
Breaking News: Best of BioWorld Science: Q1Breaking News: Best of BioWorld: Q1Breaking News: Best of BioWorld: Q1
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Skin irritation on hands
Inflammatory

Kaken licenses STAT6 program to J&J

Dec. 27, 2024
Kaken Pharmaceutical Co. Ltd. and Johnson & Johnson (J&J) have entered into a license agreement for the global development, manufacturing and commercialization of a STAT6 program for autoimmune and allergic diseases, including atopic dermatitis (AD), developed by Kaken.
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Therapeutic trends 2024 - GLP-1RAs
Endocrine/metabolic

GLP-1 receptor agonists continue their global victory tour

Dec. 27, 2024
By Anette Breindl
2024 was another banner year for GLP-1 receptor agonists (GLP-1RAs) on multiple fronts. They continued to expand into new indications, and provide their developers with both rich remuneration and scientific acclamation. There are now seven approved GLP-1RAs. Commercially, the most successful one so far is semaglutide, sold under the brand name Wegovy or Ozempic depending on the indication.
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Holiday notice

Dec. 27, 2024
In accordance with the publishing schedule, BioWorld Science was not published on Wednesday, Dec. 25, 2024, and Thursday, Dec. 26, 2024.
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Cancer

Insilico Medicine discovers new PRMT5 inhibitors

Dec. 24, 2024
Insilico Medicine Ltd. has described protein arginine N-methyltransferase 5 (PRMT5) inhibitors reported to be useful for the treatment of cancer.
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Cancer

New CBLB inhibitors disclosed in Arcus patent

Dec. 24, 2024
Arcus Biosciences Inc. has divulged E3 ubiquitin-protein ligase CBL-B (CBLB) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Ningbo Newbay Medical Technology describes new POLθ inhibitors

Dec. 24, 2024
Ningbo Newbay Medical Technology Co. Ltd. has identified DNA polymerase θ (POLθ) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Gan & Lee Pharmaceuticals divulges new antibody-drug conjugates

Dec. 24, 2024
Gan & Lee Pharmaceuticals Co. Ltd. has synthesized antibody-drug conjugates comprising a monoclonal antibody covalently linked to exatecan derivatives through a linker reported to be useful for the treatment of cancer.
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Cancer

Haihe Biopharma patents new AR-v7 degradation inducers

Dec. 24, 2024
Haihe Biopharma Co. Ltd. has disclosed benzo(hetero)cycloalkyl compounds reported to be useful for the treatment of acne, spinal and bulbar muscular atrophy, and more.
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3D illustration of heart cross section
Cardiovascular

Xentria and NYU sign licensing agreement for cardiovascular program

Dec. 24, 2024
Xentria Inc. has entered into an exclusive license agreement with New York University (NYU) securing Xentria exclusive rights related to the development of a potential disease-modifying therapeutic for cardiovascular disease.
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Cardiovascular

SYH-2062 cleared for clinic in China for hypertension

Dec. 24, 2024
CSPC Pharmaceutical Group Ltd. has gained clinical trial approval from China’s National Medical Products Administration (NMPA) for SYH-2062 injection, a double-stranded small interfering RNA (siRNA) drug to treat hypertension.
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