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BioWorld - Wednesday, May 6, 2026
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Promise Bio founders
Immune

Promise Bio raises $8.3M for immune-mediated diseases platform

Dec. 19, 2024
By Shani Alexander
Promise Bio Ltd. emerged from stealth with $8.3 million in seed investment for its precision medicine platform, which addresses immune-mediated diseases. The funding will be used to accelerate the development of the company’s technology that analyzes proteins and their post-translational modifications to predict the treatment responses of patients with immune-mediated diseases.
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Neurology/psychiatric

Alexander Shulgin Research Institute discovers new phenylalkylamine compounds

Dec. 19, 2024
Alexander Shulgin Research Institute has described phenylalkylamine compounds reported to be useful for the treatment of pain, inflammation, neurodegeneration, stroke, ischemia-reperfusion injury and psychiatric disorders.
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Infection

Methionyl-tRNA synthetase inhibitors disclosed in University of Washington patent

Dec. 19, 2024
University of Washington has divulged compounds acting as methionyl-tRNA synthetase (bacterial) inhibitors reported to be useful for the treatment of bacterial and protozoal infections.
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Cancer

Beijing Double-Crane Runchuang Technology describes new fascin inhibitors

Dec. 19, 2024
Beijing Double-Crane Runchuang Technology Co. Ltd. has identified fascin (FSCN1) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Odyssey Therapeutics divulges new CDK2/cyclin E1 inhibitors

Dec. 19, 2024
Odyssey Therapeutics Inc. has synthesized CDK2/cyclin E1 inhibitors reported to be useful for the treatment of cancer.
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Endocrine/metabolic

Chinese scientists patent new 15-hydroxyprostaglandin dehydrogenase inhibitors

Dec. 19, 2024
Researchers at Chengdu Brilliant Pharmaceutical Co. Ltd. and Scinnohub Pharmaceutical Co. Ltd. have disclosed 15-hydroxyprostaglandin dehydrogenase inhibitors reported to be useful for the treatment of diabetes, osteoporosis and more.
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AI-generated art of brain connections
Neurology/psychiatric

New nonhallucinogenic neuroplasticity-promoting therapeutics reported

Dec. 19, 2024
Researchers from Engrail Therapeutics Inc. recently described the pharmacological characterization of ENX-105, a new class of molecule that combines 5-HT1A/2A receptor agonism with D2/3 receptor antagonism, to be used for its antianhedonic and antipsychotic effects.
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Immune

Small-molecule CD40-CD40L interaction inhibitors show promise in islet transplantation mouse models

Dec. 19, 2024
Scientists from the Miller School of Medicine at the University of Miami have reported their recent work to develop small-molecule inhibitors of the CD40-CD40L (CD154) costimulatory protein-protein interaction.
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Macrophage releasing cytokines as a part of the body's immune response.
Immune

POLB-001 reduces cytokine release syndrome in mice

Dec. 19, 2024
Cancer immunotherapies are highly effective treatments for treating hematological malignancies, but usually tied to systemic toxicity, including cytokine release syndrome (CRS).
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CAR T cell attacking cancer cells
Immuno-oncology

Inceptor Bio partners with Grit Bio to advance CAR T therapy

Dec. 19, 2024
Inceptor Bio LLC and Shenzhen Grit Biotechnology Co. Ltd. have established a strategic partnership to advance IB-T101, a CAR T therapy targeting solid tumors.
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