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BioWorld - Sunday, April 19, 2026
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Microneedle array vaccine
Vaccines

The next pandemic: Speeding development and stretching supplies

April 14, 2020
By Anette Breindl
“Vaccines, obviously, are the ultimate solution for pandemics,” Rino Rappuoli told BioWorld. They have, he added, “already eliminated a lot of pandemic threats – smallpox, influenza, poliomyelitis.”
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Natural killer cell
Drugs

The next pandemic: Firebreaks and host-directed therapies

April 14, 2020
By Anette Breindl
Specific therapies against a new disease take time to develop. But there are methods that can speed up that development.
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SARS-CoV-2 molecular diagnostic
Diagnostics

The next pandemic: Excess testing capacity essential, but cost question not yet answered

April 14, 2020
By Mark McCarty
There will be lessons learned aplenty when the COVID-19 pandemic finally breaks, including how serological and molecular testing can be used to maximum effect to corral a future pandemic.
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1918-19 Spanish flu patient, paramedics, ambulance
Surveillance

The next pandemic: Death, taxes and zoonotic spillover

April 14, 2020
By Anette Breindl
“In any crisis, leaders have two equally important responsibilities: solve the immediate problem and keep it from happening again."
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Blood cells and bacteria

Sepsis study may yield new treatment strategies

April 7, 2020
By John Fox
Indian scientists have discovered a previously unknown mechanism underlying life-threatening sepsis and proposed a new treatment strategy centered upon cell-free chromatin (cfCh), they reported in the March 4, 2020, edition of PLOS ONE.
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Scientific data illustration
It’s not FAIR!

Accelerated by COVID-19, science changes will outlast pandemic

April 7, 2020
By Anette Breindl
COVID-19 has disrupted science in the way it has disrupted everything else. In the short term, universities have largely closed shop as a way to maximize social distancing, and lots of science – or at least, lots of bench work – is not getting done.
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3D model of coronavirus spike
Basis for antibodies, vaccines

Structural studies show similarities and differences in SARS, COVID-19 receptor binding

March 31, 2020
By Nuala Moran
LONDON – Two papers published online in Nature following accelerated peer review provide fine detail of how the spike protein on the COVID-19 coronavirus binds to the angiotensin converting enzyme 2 (ACE2) through which it infects its human host.
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Targeting glycosylated PD-1 induces potent antitumor immunity

March 24, 2020
By John Fox
Targeting glycosylated PD-1 immune checkpoint may be a promising new cancer immunotherapeutic strategy, according to a collaborative study led by Taiwanese researchers, which was reported online in Cancer Research.
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Map illustrating origin and spread of coronavirus

Undetected cases are major source of pandemic spread

March 17, 2020
By Anette Breindl
Undetected cases were a major driver of the early spread of SARS-CoV-2 in Wuhan, China, despite being less infectious on a case-by-case basis, according to a modeling study published in the March 16, 2020, online issue of Science.
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Airport traveler wearing mask, pulling suitcase
COVID-19

Opportunity to control epidemic narrowing, as epidemiology gaps frustrate researchers

Feb. 25, 2020
By Nuala Moran
LONDON – Six weeks on from the initial alert, “the window of opportunity” to control the COVID-19 epidemic is “narrowing,” according to the latest assessment from WHO Director General Tedros Adhanom Ghebreyesus.
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