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BioWorld - Saturday, June 27, 2026
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AACR 2020

Phosphatases are yin to kinases’ yang

May 5, 2020
By Anette Breindl
The activity of many proteins is controlled through phosphorylation by kinases and dephosphorylation by phosphatases.
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Vero E6 cell infected with SARS-CoV-2
Thwarting the hijacker

In vitro study gives ‘blueprint’, drug leads for SARS-CoV-2

May 5, 2020
By Anette Breindl
A multi-institutional group led by the University of California at San Francisco’s Quantitative Biosciences Institute (QBI) has identified more than 200 host proteins that interacted with SARS-CoV-2 viral proteins during infection, creating “a blueprint of how SARS-CoV-2 hijacks human cells.”
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Antibiotic resistance map of U.S.

Climate crisis is chronicle of a death foretold

May 5, 2020
By Anette Breindl
The climate crisis in the time of COVID-19 illustrates the difference between the important and the urgent. There is, of course, no alternative to focusing on the current pandemic. But at the same time, the SARS-CoV-2 coronavirus has not changed the fact that the climate crisis is a coming wave whose health consequences will ultimately dwarf those of any single infectious agent.
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Coronavirus and DNA

Cooperative research effort taking aim at genetics affecting COVID-19 infection

April 28, 2020
By Nuala Moran
LONDON – Leading genome sequencing groups are launching the first meta-analysis in the hunt for genetic factors that explain why some people have worse COVID-19 symptoms than others, after agreeing to share patient sequence data from around the world.
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Microneedle array vaccine
Vaccines

The next pandemic: Speeding development and stretching supplies

April 14, 2020
By Anette Breindl
“Vaccines, obviously, are the ultimate solution for pandemics,” Rino Rappuoli told BioWorld. They have, he added, “already eliminated a lot of pandemic threats – smallpox, influenza, poliomyelitis.”
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Natural killer cell
Drugs

The next pandemic: Firebreaks and host-directed therapies

April 14, 2020
By Anette Breindl
Specific therapies against a new disease take time to develop. But there are methods that can speed up that development.
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SARS-CoV-2 molecular diagnostic
Diagnostics

The next pandemic: Excess testing capacity essential, but cost question not yet answered

April 14, 2020
By Mark McCarty
There will be lessons learned aplenty when the COVID-19 pandemic finally breaks, including how serological and molecular testing can be used to maximum effect to corral a future pandemic.
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1918-19 Spanish flu patient, paramedics, ambulance
Surveillance

The next pandemic: Death, taxes and zoonotic spillover

April 14, 2020
By Anette Breindl
“In any crisis, leaders have two equally important responsibilities: solve the immediate problem and keep it from happening again."
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Blood cells and bacteria

Sepsis study may yield new treatment strategies

April 7, 2020
By John Fox
Indian scientists have discovered a previously unknown mechanism underlying life-threatening sepsis and proposed a new treatment strategy centered upon cell-free chromatin (cfCh), they reported in the March 4, 2020, edition of PLOS ONE.
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Scientific data illustration
It’s not FAIR!

Accelerated by COVID-19, science changes will outlast pandemic

April 7, 2020
By Anette Breindl
COVID-19 has disrupted science in the way it has disrupted everything else. In the short term, universities have largely closed shop as a way to maximize social distancing, and lots of science – or at least, lots of bench work – is not getting done.
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