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BioWorld - Monday, May 4, 2026
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BioWorld Asia, Science
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Glucose testing

New therapeutic target for blood sugar control identified

Sep. 8, 2020
By John Fox
An Australian study led by University of Melbourne scientists has identified a previously unknown role for the hepatokine, sparc-related modular calcium-binding protein 1 (SMOC1), in suppressing hepatic glucose production.
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Petri dish and capsules

Singapore-based researchers find a SMART way to reduce bacterial antibiotic resistance

Aug. 25, 2020
By David Ho
HONG KONG – Researchers from the Massachusetts Institute of Technology’s (MIT) research enterprise in Singapore have found a way to not just reverse antibiotic resistance but also increase sensitivity in some bacteria, using hydrogen sulfide.
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Science-8-14

Acupuncture shown to regulate inflammation in mice

Aug. 18, 2020
By John Fox
A Sino-U.S. collaborative study has demonstrated that acupuncture regulates inflammation by activating pro- or anti-inflammatory signaling pathways, while mitigating cytokine storms in mice with systemic inflammation, the study authors reported in the Aug. 12, 2020, edition of Neuron.
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Herd immunity illustration

COVID-19: Trying for herd immunity without vaccine ‘unethical’ and ‘unachievable’

July 7, 2020
By Anette Breindl
A large epidemiological study published in the July 6, 2020, advance online issue of The Lancet found that most individuals who became infected with SARS-CoV-2 developed antibodies to the virus, confirming that infection usually results in at least a short-term immune response.
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CAR T cells attacking senescent cells

CAR T cells target senescence marker, ameliorate cancer, fibrosis

June 23, 2020
By Anette Breindl
By targeting chimeric antigen receptors (CARs) to a senescence marker, researchers at Memorial Sloan-Kettering Cancer Center have developed a CAR T cell that had beneficial effects in mouse models of both liver fibrosis and lung cancer.
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Fidget spinner toy and diagnostic fidget spinner

Centrifugation can be child’s play with fidget spinners

June 2, 2020
By John Fox
Fidget spinners are hand-held toys based on a roller bearing and three weighted lobes, which can spin freely, creating centrifugal force when activated manually.
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Immune cell density plot
Reversal of ApoE4tune

Germline ApoE variants affect melanoma trajectory

May 26, 2020
By Anette Breindl
Variants in the APOE gene are the strongest genetic risk factor for developing Alzheimer’s disease (AD). Now, researchers at Rockefeller University have demonstrated that APOE variants also affected the risk of progression and metastasis as well as the response to immunotherapy, in melanoma.
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AACR 2020

Phosphatases are yin to kinases’ yang

May 5, 2020
By Anette Breindl
The activity of many proteins is controlled through phosphorylation by kinases and dephosphorylation by phosphatases.
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Vero E6 cell infected with SARS-CoV-2
Thwarting the hijacker

In vitro study gives ‘blueprint’, drug leads for SARS-CoV-2

May 5, 2020
By Anette Breindl
A multi-institutional group led by the University of California at San Francisco’s Quantitative Biosciences Institute (QBI) has identified more than 200 host proteins that interacted with SARS-CoV-2 viral proteins during infection, creating “a blueprint of how SARS-CoV-2 hijacks human cells.”
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Antibiotic resistance map of U.S.

Climate crisis is chronicle of a death foretold

May 5, 2020
By Anette Breindl
The climate crisis in the time of COVID-19 illustrates the difference between the important and the urgent. There is, of course, no alternative to focusing on the current pandemic. But at the same time, the SARS-CoV-2 coronavirus has not changed the fact that the climate crisis is a coming wave whose health consequences will ultimately dwarf those of any single infectious agent.
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