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BioWorld - Monday, June 16, 2025

Drug resistance

Home » Topics » Science » Drug resistance
  • Klebsiella pneumoniae colonies petri dish
    Feb. 14, 2025

    Boronic acid inhibitors restore cefepime efficacy in multidrug-resistant KPC-producing K. pneumoniae

    The boronic acid transition state inhibitors S-02030 and MB-076 were strategically designed to be active against cephalosporinases and carbapenemases, especially KPC (Klebsiella pneumoniae carbapenemase).
  • Feb. 14, 2025

    APD-94, a dual functional inhibitor of Bmi-1 and tubulin

    Researchers from Hebei Normal University and affiliated organizations presented the discovery and preclinical characterization of a novel B lymphoma Mo-MLV insertion region 1 (Bmi-1) expression inhibitor, APD-94, designed as an agent that could potentially overcome drug resistance in patients with colorectal cancer.
  • Bacterial colonies in petri dishes
    Feb. 13, 2025

    Gates Foundation, Novo Nordisk Foundation and Wellcome set sights on antimicrobial resistance

    The Gates Foundation, Novo Nordisk Foundation and Wellcome have announced the launch of the Gram-Negative Antibiotic Discovery Innovator (Gr-ADI), a $50 million investment that will focus on combatting antimicrobial resistance (AMR) caused by a specific range of bacteria that are among the leading contributors to AMR-associated deaths.
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Blog Posts

  • Feb. 4, 2015
    By Mari Serebrov

    Listening to the voice that matters

  • June 5, 2014
    By Randy Osborne

    ASCO strides provide cold comfort

  • May 30, 2014
    By Michael Fitzhugh

    Capturing cancer drugs' true value calls for clear thinking

  • June 7, 2013
    By Randy Osborne

    Oh, Give it Iressa! Nope: ‘Bad Pharma’ Firms Need to Tell More

  • April 2, 2012
    By Anette Breindl

    Want Better Data? Align Professional Incentives

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