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BioWorld - Saturday, January 31, 2026
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Microbiome illustration

Gut microbiome affects protein folding in brain, muscles

May 7, 2021
By Anette Breindl
Using the roundworm C. elegans as a "living test tube," researchers at the University of Florida have identified specific gut bacteria that promoted protein misfolding throughout the body, as well as others that were protective.
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Tau protein in Alzheimer's disease

Study identifies four Alzheimer’s subtypes

May 5, 2021
By John Fox
An international collaborative study led by scientists at Sweden’s Lund University has classified Alzheimer’s disease into four distinct subtypes, which has important implications for the management of the progressive neurodegenerative disease, the authors reported in the April 29, 2021, edition of Nature Medicine.
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Gene editing illustration

Prime, base editing are "finer scalpels" in dystrophy

May 5, 2021
By Nuala Moran
New genome editing techniques have opened up the number of potential mutations that could be addressed in the inherited muscle wasting disorder Duchenne muscular dystrophy, while also reducing the probability of inducing off target effects.
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T cells

Adrenaline release immobilizes immune cell responses

May 4, 2021
By Subhasree Nag
Using advanced intravital microscopy to visualize immune cell movement within the tissues, investigators at the Peter Doherty Institute for Infection and Immunity, Melbourne have discovered that noradrenaline causes a dramatic paralysis of immune cell movement.
Read More
T cells

Adrenaline release immobilizes immune cell responses

May 4, 2021
By Subhasree Nag
Using advanced intravital microscopy to visualize immune cell movement within the tissues, investigators at the Peter Doherty Institute for Infection and Immunity, Melbourne have discovered that the neurotransmitter noradrenaline produced by the sympathetic nervous system causes a dramatic paralysis of immune cell movement.
Read More
Hands holding petri dish

Mitochondrial peptide causes septic shock nosocomials, mortality

May 4, 2021
By John Fox
A Korean/U.S. collaborative study has shown that increased circulating mitochondrial N-formyl peptide contributes to development of secondary hospital-acquired (nosocomial) infections and increased mortality in septic shock patients who survived the early hyperinflammatory phase.
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Liver illustration

Fat no proxy for quality in transplant livers

April 30, 2021
By Anette Breindl
Researchers have gained new insights into what makes for transplantable livers – and what doesn’t. In a clinical trial of 12 livers, a team from Massachusetts General Hospital showed that both livers with high fat content and those without could be viable for transplantation.
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BioWorld MedTech’s Neurology Extra for April 30, 2021

April 30, 2021
By Andrea Applegate
Keeping you up to date on recent developments in neurology, including: Detecting brain damage in babies earlier with new infrared scanner; VR treatment for PTSD to be evaluated in clinical trial; NIH study identifies diverse spectrum of neurons that govern movement.
Read More
T cells

Adrenaline release immobilizes immune cell responses

April 30, 2021
By Subhasree Nag
Using advanced intravital microscopy to visualize immune cell movement within the tissues, investigators at the Peter Doherty Institute for Infection and Immunity, Melbourne have discovered that the neurotransmitter noradrenaline produced by the sympathetic nervous system causes a dramatic paralysis of immune cell movement.
Read More

Preclinical through phase III, new COVID-19 therapy trials ramp up

April 30, 2021
By Michael Fitzhugh and Anette Breindl
Urgency to meet the world's worsening load of COVID-19 cases appeared unflagging Thursday, with four new trials kicking off to evaluate treatments aimed at keeping people from progressing to worsened disease and reports on two new variant-focused efforts yielding signs of preclinical promise.
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