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BioWorld - Saturday, January 3, 2026
Home » Topics » Disease categories and therapies » Cancer

Cancer
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Cancer

Hangzhou Baicreat Pharma-Tech describes new POLθ inhibitors

Nov. 5, 2025
Hangzhou Baicreat Pharma-Tech Co. Ltd. has identified DNA polymerase θ (POLθ) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Shanghai Apeiron Biotechnology patents new PRMT5 degradation inducers

Nov. 5, 2025
Shanghai Apeiron Biotechnology Co. Ltd. has disclosed proteolysis targeting chimeras (PROTACs) reported to be useful for the treatment of cancer.
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Cancer

Prelude signs option deal, prioritizes JAK2 and KAT6A programs

Nov. 5, 2025
No Comments
Prelude Therapeutics Inc. has outlined its plans to prioritize programs within its pipeline and announced an exclusive option agreement with Incyte Corp.
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3D illustration demonstrating antibody-drug conjugate.
Immuno-oncology

Bispecific antibody-drug conjugate Gensci-143 shows promise in solid tumors

Nov. 5, 2025
No Comments
Changchung Genescience Pharmaceutical Co. Ltd., reported effects of the bispecific antibody-drug conjugate (ADC) of Gensci-143, is in metastatic castration-resistant prostate cancer (mCRPC) and other solid tumors.
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Immuno-oncology

Glycan-targeting ADC shows preclinical activity against HER2-low gastric cancer

Nov. 5, 2025
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Advanced gastric cancer continues to pose a significant medical challenge because of the scarcity of effective treatments and the frequent development of resistance to available drugs.
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Cancer cells being destroyed by immunotherapy
Immuno-oncology

Leukogene’s LTI-214 designated orphan drug for AML

Nov. 5, 2025
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Leukogene Therapeutics Inc.’s lead product candidate LTI-214 (M2T-CD33) has been awarded orphan drug designation by the FDA for the treatment of acute myeloid leukemia (AML).
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Celltrion, Portrai in $87M R&D deal to discover new drug targets

Nov. 4, 2025
By Marian (YoonJee) Chu
No Comments
Celltrion Inc. announced Oct. 29 the signing of an $87.75 million joint drug R&D agreement with AI and spatial transcriptome-based biotech Portrai Inc.
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Illustration of nasopharyngeal carcinoma

Lepu’s MRG-003 cleared as China’s first EGFR ADC for advanced NPC

Nov. 4, 2025
By Marian (YoonJee) Chu
No Comments
Lepu Biopharma Co. Ltd. said Oct. 30 it won Chinese approval of a novel antibody-drug conjugate (ADC), Meiyouheng (becotatug vedotin injection), making it China’s first epidermal growth factor receptor (EGFR)-directed ADC for advanced nasopharyngeal cancer (NPC).
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Stock chart, red down arrow

Incyte aboard, SMARCA2 shift by Prelude enshrouds Foghorn

Nov. 4, 2025
By Randy Osborne
No Comments
Just as investors were looking ahead to news by year-end on Prelude Therapeutics Inc.’s SMARCA2-targeted degraders, the firm said work in the space will be halted, with efforts shifting toward the mutant selective JAK2V617F JH2 inhibitor program by way of a new deal with Incyte Corp.
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Cancer

Innocare Pharma divulges new CBLB inhibitors

Nov. 4, 2025
Beijing Innocare Pharma Tech Co. Ltd. has synthesized E3 ubiquitin-protein ligase CBL-B (CBLB) inhibitors reported to be useful for the treatment of cancer.
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