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Home » Topics » Disease categories and therapies » Cancer

Cancer
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Cancer

Wigen Biomedicine Technology discovers new PKMYT1 inhibitors

May 30, 2025
Wigen Biomedicine Technology (Shanghai) Co. Ltd. has described Myt1 kinase (PKMYT1) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Sichuan Kelun-Biotech Biopharmaceutical describes new FAPα inhibitors

May 30, 2025
Sichuan Kelun-Biotech Biopharmaceutical Co. Ltd. has identified radiolabeled or nonradiolabeled compounds acting as fibroblast activation protein-α (FAPα) inhibitors reported to be useful for the diagnosis and treatment of cancer.
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Cancer

Shanghai Qilu Pharmaceutical divulges new PARG inhibitors

May 30, 2025
Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. has synthesized poly(ADP-ribose) glycohydrolase (PARG) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Shenzhen Zhongge Biotechnology patents new PARP-7 inhibitors

May 30, 2025
Shenzhen Zhongge Biotechnology Co. Ltd. has disclosed protein mono-ADP-ribosyltransferase TIPARP (PARP-7; ARTD14) inhibitors reported to be useful for the treatment of inflammatory disorders, immunological disorders, viral infections and cancer.
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Illustration of tumor in the liver
Biomarkers

DNAJC7 involved in hepatocellular carcinoma progression and prognosis

May 30, 2025
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Hepatocellular carcinoma (HCC) is among the leading causes of cancer-related deaths worldwide due to lack of effective diagnosis at early stages and limited comprehension of its pathogenesis, thus limiting the development of effective treatments.
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Doctor points at molecular structure
Cancer

Chinese researchers describe first-in-class PRMT1 degrader

May 30, 2025
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PRMT1 is a key enzyme that catalyzes asymmetric dimethylation of arginine residues and overexpressed in various cancers and inflammatory diseases. While current PRMT1 inhibitors lack specificity and effectiveness, targeted degradation of PRMT1 offers a potential strategy to treat PRMT1-driven conditions and explore its nonenzymatic roles.
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Cancer cell, dropper, test tubes
Cancer

Silexion’s SIL-204 shows promise in pancreatic, colorectal and lung cancer cell lines

May 30, 2025
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Silexion Therapeutics Corp. has released preclinical data demonstrating the efficacy of its next-generation RNA interference (RNAi) therapeutic candidate, SIL-204, against human pancreatic, colorectal and lung cancer cell lines.


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Cancer

Novel CLK2/3 inhibitor with strong antiproliferative activity disclosed

May 30, 2025
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Targeting CDC-like kinases 2 and 3 (CLK2 and CLK3) has emerged as an effective therapeutic strategy in cancer treatment, with several compounds currently in clinical development.
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3D illustration of tumor
Immuno-oncology

Proof of concept demonstrated for Voltron’s VTX-0P4 in PSCA-expressing tumors

May 30, 2025
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Voltron Therapeutics Inc. has reported data from a study evaluating VTX-0P4.
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Cancer

ZNF101 unveiled as a therapeutic target in TNBC

May 30, 2025
No Comments
Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype with a lack of efficacious therapeutic approaches.
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