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BioWorld - Monday, June 15, 2026
Home » Topics » Disease categories and therapies » Neurology/psychiatric

Neurology/psychiatric
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Chance Pharma licenses inhalable PD treatment from Acorda in $140M deal

May 16, 2023
By Zhang Mengying
Chance Pharmaceuticals Co. Ltd. acquired greater China rights to Inbrija (levodopa inhalation powder), used to manage Parkinson’s disease (PD), from Acorda Therapeutics Inc. in a deal worth as much as $140 million.
Read More
Elderly man with clenched hands holding head

US FDA approves Rexulti as first drug for agitation in Alzheimer’s dementia

May 16, 2023
By Karen Carey and Tamra Sami
On its May 10 PDUFA date, the U.S. FDA approved serotonin-dopamine modulator Rexulti (brexpiprazole) from Otsuka Pharmaceutical Co. Ltd. and H. Lundbeck A/S for agitation in Alzheimer’s dementia, marking the first approved treatment for the indication.
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Brain and encephalography

JCR partners with Angelini on biologic therapies for epilepsy

May 16, 2023
By Zhang Mengying
Angelini Pharma SpA and JCR Pharmaceuticals Co. Ltd. signed an exclusive worldwide agreement for the development and commercialization of biologic therapies for epilepsy based on the J-Brain Cargo technology.
Read More
Stroke illustration: brain, artery, neurons
Neurology/Psychiatric

GluN2B-NMDA receptor antagonism proves effective in cerebral ischemia models

May 16, 2023
N-Methyl-D-aspartate (NMDA) receptors are essential components of the glutamatergic pathways in the central nervous system. NMDA receptors comprise two GluN1 subunits and two GluN2 subunits. Of the latter, the GluN2B subunit is involved in synapse development and plasticity, and cognitive function.
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Neon brain
Neurology/Psychiatric

Giving organoids in vivo environment improves brain modeling

May 16, 2023
By Xavier Bofill Bruna
Implanting brain organoids into the brains of mice may allow the more realistic study of microglial cells during both healthy and disease states. This is what researchers from the Salk Institute and their collaborators found in a study published on May 11, 2023, in Cell.
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Brain and encephalography

JCR partners with Angelini on biologic therapies for epilepsy

May 15, 2023
By Zhang Mengying
Angelini Pharma SpA and JCR Pharmaceuticals Co. Ltd. signed an exclusive worldwide agreement for the development and commercialization of biologic therapies for epilepsy based on the J-Brain Cargo technology.
Read More
Cross section of brain
Newco news

Nido Biosciences raises $109M to drug novel targets in neurological disease

May 15, 2023
By Cormac Sheridan
Nido Biosciences Inc. emerged from stealth by unveiling $109 million in series A and B equity funding and a clinical-stage program in spinal and bulbar muscular atrophy.
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PET imaging of RELN-COLBOS (H3447R) carrier brain showing limited aggregation of tau
Neurology/Psychiatric

Reelin’ in druggable protective pathways with second Alzheimer’s ‘escapee’

May 15, 2023
By Anette Breindl
Investigators have identified a second individual who remained cognitively normal into his late 60s despite having the PSEN1 E280A mutation, which causes a familial version of early-onset Alzheimer’s disease (AD). The likely source of protection, a mutation in a gene called Reelin, is distinct from the protective mechanism identified in the first case of an individual who was protected from the effects of PSEN1 E280A. That case was reported in 2019.
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Brain and encephalography
Neurology/Psychiatric

Angelini and JCR collaborate to develop and commercialize novel biologic therapies for epilepsy

May 12, 2023
Angelini Pharma SpA and JCR Pharmaceuticals Co. Ltd. have entered into an exclusive global development and commercialization agreement for the development of novel biologic therapies that applies J-Brain Cargo blood-brain barrier penetrating technology for the treatment of epilepsy, applying undisclosed effectors.
Read More

Chance Pharma licenses inhalable PD treatment from Acorda in $140M deal

May 11, 2023
By Zhang Mengying
Chance Pharmaceuticals Co. Ltd. acquired greater China rights to Inbrija (levodopa inhalation powder), used to manage Parkinson’s disease (PD), from Acorda Therapeutics Inc. in a deal worth as much as $140 million.
Read More
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