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BioWorld - Wednesday, July 16, 2025
Home » Topics » Disease categories and therapies » Respiratory

Respiratory
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Immune

TAVO-101, a potent anti-TSLP antibody with extended half-life

Dec. 19, 2024
Researchers from Tavotek Biotherapeutics Inc. described the discovery and preclinical characterization of TAVO-101.
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GC Biopharma to buy Abo Holdings for ₩138B, grow US plasma biz

Dec. 17, 2024
By Marian (YoonJee) Chu
GC Biopharma Corp. will buy plasma collector Abo Holdings Inc. in a ₩138 billion (US$96.28 million) cash acquisition as the vaccine and plasma-derived medicinal products developer works to accelerate entry of Alyglo (IVIG-SN 10%) in the U.S., where it was approved last year.
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Kyorin in-licenses Bayer’s phase II sleep apnea drug for €85M+

Dec. 17, 2024
By Tamra Sami
Kyorin Pharmaceutical Co. Ltd. has acquired Bayer AG’s phase II obstructive sleep apnea candidate, BAY-2925976, in a deal worth €85M (US$89.3 million) plus sales-based royalties and commercial milestones.
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Puretech’s modified pirfenidone impresses in phase IIb IPF trial

Dec. 16, 2024
By Nuala Moran
Puretech Health plc has announced phase IIb data showing its reformulation of pirfenidone has improved the tolerability and increased the efficacy of the marketed antifibrotic in the treatment of idiopathic pulmonary fibrosis. The tweak on the original molecule involved substituting three hydrogen atoms with three of the heavier counterpart, deuterium, improving stability, whilst retaining the antifibrotic effect.
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GC Biopharma to buy Abo Holdings for ₩138B, grow US plasma biz

Dec. 13, 2024
By Marian (YoonJee) Chu
GC Biopharma Corp. will buy plasma collector Abo Holdings Inc. in a ₩138 billion (US$96.28 million) cash acquisition as the vaccine and plasma-derived medicinal products developer works to accelerate entry of Alyglo (IVIG-SN 10%) in the U.S., where it was approved last year.
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Lungs

Trial’d on for size, Trevi’s Haduvio fits nice in IPF cough

Dec. 12, 2024
By Randy Osborne
News that Trevi Therapeutics Inc. got the size just right of the phase IIb Coral trial with Haduvio (oral nalbuphine extended release) led the company’s shares (NASDAQ:TRVI) to close Dec. 12 at $3.60, up $1.11, or 45%, after trading as high as $4.60.
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Europlaz neonatal flow sensor

Europlaz develops neonatal device to save babies' lives

Dec. 11, 2024
By Shani Alexander
Europlaz Technologies Ltd. has developed a new neonatal flow sensor that could help improve neonatal care and save the lives of babies born prematurely. The company created an integrated ‘sidestream’ carbon dioxide (CO2) sampling port, which when added to the side of its existing neonatal flow sensor will enable clinicians to monitor CO2 being exhaled from the baby’s lungs to better inform care.
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Illustration of receptor binding site of the A/Texas/37/2024 hemagglutinin Leu226 mutant
Infection

A single mutation in H5N1 is all that’s needed for easier transmissibility

Dec. 10, 2024
By Mar de Miguel
Although it does not generally infect humans, a single mutation of the H5N1 virus in the highly pathogenic avian and bovine clade 2.3.4.4b could overcome this barrier and possibly trigger a pandemic.
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Respiratory

Haisco Pharmaceutical discovers new integrin αvβ1 and αvβ6 antagonists for IPF

Dec. 10, 2024
Haisco Pharmaceutical Group Co. Ltd. has described compounds acting as integrin αvβ1 and/or αvβ6 antagonists reported to be useful for the treatment of idiopathic pulmonary fibrosis (IPF).
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Pediatric exam

Enanta logs phase II RSV win with zelicapavir

Dec. 9, 2024
By Randy Osborne
Enanta Pharmaceuticals Inc. hit the mark that Wall Street hoped for, and details rolled out in top-line results from the first-in-pediatrics phase II study evaluating once-daily, oral zelicapavir in hospitalized and non-hospitalized children aged 28 days to 36 months with respiratory syncytial virus (RSV).
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