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Home » Topics » Disease categories and therapies » Respiratory

Respiratory
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Lungs
Respiratory

SYH-2059 to enter trials in China for interstitial lung disease

Jan. 8, 2025
CSPC Pharmaceutical Group Ltd. has obtained clearance from China’s National Medical Products Administration (NMPA) to conduct clinical trials in China of SYH-2059 tablets for interstitial lung disease, including idiopathic pulmonary fibrosis and progressive pulmonary fibrosis.
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Photo of Jaeyong Ahn and Jean-Francois Toussant in signing ceremony

Sanofi expands SK Bio deal, starts phase III of GBP-410

Dec. 24, 2024
By Marian (YoonJee) Chu
SK Bioscience Co. Ltd. won €50 million (₩75.5 billion, US$52.03 million) up front from Sanofi SA to expand an earlier agreement to develop and commercialize novel pneumococcal conjugate vaccines (PCVs). The first deal resulted in GBP-410 (SP-0202), its pediatric 21-valent PCV candidate that moved into phase III study last week.
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Photo of Jaeyong Ahn and Jean-Francois Toussant in signing ceremony

Sanofi expands SK Bio deal, starts phase III of GBP-410

Dec. 23, 2024
By Marian (YoonJee) Chu
SK Bioscience Co. Ltd. won €50 million (₩75.5 billion, US$52.03 million) up front from Sanofi SA to expand an earlier agreement to develop and commercialize novel pneumococcal conjugate vaccines (PCVs). The first deal resulted in GBP-410 (SP-0202), its pediatric 21-valent PCV candidate that moved into phase III study last week.
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Alyftrek specs check out in cystic fibrosis as Vertex wins FDA nod

Dec. 23, 2024
By Randy Osborne
Vertex Pharmaceuticals Inc.’s chief operating officer Stuart Arbuckle said during the Stifel Healthcare Conference in November that his firm’s launch last year of Casgevy (exagamglogene autotemcel) for sickle cell disease and transfusion-dependent beta-thalassemia “was the beginning of diversifying on top of our cystic fibrosis [CF] base” – a base that itself continues to grow.
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Inflammatory

Deepcure discovers oral STAT6 inhibitors for type 2 inflammatory diseases

Dec. 20, 2024
Deepcure Inc. has discovered potent, selective oral small-molecule inhibitors of STAT6. These next-generation STAT6 inhibitors have demonstrated promising oral bioavailability, cell permeability and metabolic stability, and do not target STAT6 for degradation.
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Immune

TAVO-101, a potent anti-TSLP antibody with extended half-life

Dec. 19, 2024
Researchers from Tavotek Biotherapeutics Inc. described the discovery and preclinical characterization of TAVO-101.
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GC Biopharma to buy Abo Holdings for ₩138B, grow US plasma biz

Dec. 17, 2024
By Marian (YoonJee) Chu
GC Biopharma Corp. will buy plasma collector Abo Holdings Inc. in a ₩138 billion (US$96.28 million) cash acquisition as the vaccine and plasma-derived medicinal products developer works to accelerate entry of Alyglo (IVIG-SN 10%) in the U.S., where it was approved last year.
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Kyorin in-licenses Bayer’s phase II sleep apnea drug for €85M+

Dec. 17, 2024
By Tamra Sami
Kyorin Pharmaceutical Co. Ltd. has acquired Bayer AG’s phase II obstructive sleep apnea candidate, BAY-2925976, in a deal worth €85M (US$89.3 million) plus sales-based royalties and commercial milestones.
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Puretech’s modified pirfenidone impresses in phase IIb IPF trial

Dec. 16, 2024
By Nuala Moran
Puretech Health plc has announced phase IIb data showing its reformulation of pirfenidone has improved the tolerability and increased the efficacy of the marketed antifibrotic in the treatment of idiopathic pulmonary fibrosis. The tweak on the original molecule involved substituting three hydrogen atoms with three of the heavier counterpart, deuterium, improving stability, whilst retaining the antifibrotic effect.
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GC Biopharma to buy Abo Holdings for ₩138B, grow US plasma biz

Dec. 13, 2024
By Marian (YoonJee) Chu
GC Biopharma Corp. will buy plasma collector Abo Holdings Inc. in a ₩138 billion (US$96.28 million) cash acquisition as the vaccine and plasma-derived medicinal products developer works to accelerate entry of Alyglo (IVIG-SN 10%) in the U.S., where it was approved last year.
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