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BioWorld - Thursday, April 30, 2026
Home » Topics » Drug design, drug delivery and technologies, BioWorld Science

Drug design, drug delivery and technologies, BioWorld Science
Drug design, drug delivery and technologies, BioWorld Science RSS Feed RSS

DNA, drug development concept art.
Drug Design, Drug Delivery & Technologies

Moderna and Generation Bio collaborate to develop nonviral genetic medicines

March 24, 2023
Moderna Inc. and Generation Bio Co. have entered into a strategic collaboration to combine Moderna’s biological and technical expertise...
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Drug research
Drug Design, Drug Delivery & Technologies

Charm Therapeutics and Bristol Myers Squibb establish drug discovery collaboration

March 21, 2023
Charm Therapeutics Ltd. has entered into a strategic discovery collaboration with Bristol Myers Squibb Co. for the identification and optimization of compounds against Bristol Myers Squibb's selected targets.
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3D concept image of nanoparticle layers
Immuno-oncology

Talem Therapeutics collaborates with Libera Bio to develop novel antibodies for use with MPN delivery

March 16, 2023
Talem Therapeutics LLC, an independently...
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Concept art for RNA interference, gene silencing.
Neurology/Psychiatric

Switch Therapeutics launches with focus on conditionally activated siRNA molecules

March 14, 2023
Switch Therapeutics Inc. has announced its launch following US$52 million of financing. The company was founded on the premise of a new type of RNA medicine that integrates nucleic acid nanotechnology and RNA interference (RNAi) science.
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DNA illustration
Drug Design, Drug Delivery & Technologies

Epic Bio achieves persistent gene activation using GEMS platform

March 14, 2023
Epic Bio (Epicrispr Biotechnologies Inc.) has presented new data demonstrating the achievement of persistent gene activation using its Gene Expression Modulation System (GEMS) platform.
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Photomicrograph of bone marrow aspirate showing myeloblasts of acute myeloid leukemia
Cancer

A new dual strategy for acute myeloid leukemia

March 13, 2023
By Mar de Miguel
Two molecules that affected the cell cycle only of acute myeloid leukemia (AML) cells could be used as a clinical strategy against this pathology. Scientists at Memorial Sloan Kettering Cancer Center and Harvard University have discovered that DEG-35 and DEG-77 arrested the cell cycle and promoted cell differentiation and apoptosis in these cells.
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Gene editing of human embryos
Genetic/Congenital

Standard method for evaluating germline edits has large blind spots

March 10, 2023
By Xavier Bofill Bruna
The intended use of gene editing tools on pre-implantation human embryos would be to avoid the development of congenital diseases in the upcoming baby. But it may have its own risks. Those risks were illustrated in a publication in the March 7, 2023, issue of Nature Communications, where researchers from the Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University (OHSU) showed that the method that is most frequently used for evaluating the effects of gene editing zygotes did not always result in an accurate picture of those edits.
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Drug Design, Drug Delivery & Technologies

Ampersand Biomedicines set to develop programmable, more targeted therapeutics

March 8, 2023
Flagship Pioneering Inc. has unveiled Ampersand Biomedicines, a company creating programmable medicines that are safer, more tolerable and effective by acting at the site of disease. Flagship has initially committed US$50 million to advance Ampersand's Address, Navigate, Design (AND) Platform and develop an initial pipeline of medicines across a range of disease areas.
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Biocom space-panel
Drug Design, Drug Delivery & Technologies

Biocom 2023: There’s science going on 250 miles above your head

March 2, 2023
By Brian Orelli
Performing experiments and potentially manufacturing products in space offers some unique advantages in a near-zero gravity environment. Space changes buoyancy, hydrostatic pressure and convective heat flow. Researchers are studying how those changes affect cells, but also looking to take advantage of the changes to create products in manufacturing processes that wouldn’t be possible on earth.
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Drug Design, Drug Delivery & Technologies

FDA clears IND application for product utilizing doggybone DNA

March 1, 2023
Touchlight Genetics Ltd. has announced FDA clearance of an IND application for a product utilizing doggybone DNA (dbDNA).
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