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BioWorld MedTech’s Diagnostics Extra for May 28, 2020

May 28, 2020
By Meg Bryant and Anette Breindl
Keeping you up to date on recent developments in diagnostics, including: Double-contrast probe detects tiny tumors on MRI, Identifying risk of ischemic stroke, T cell aging induces broader senescence, ALK is a candidate thinness gene.
Read More
Fidget spinner toy and diagnostic fidget spinner

Centrifugation can be child’s play with fidget spinners

May 28, 2020
By John Fox
Fidget spinners are hand-held toys based on a roller bearing and three weighted lobes, which can spin freely, creating centrifugal force when activated manually. Generating centrifugal force with a fidget spinner takes neither electricity nor trained staff. And that has suggested to several researchers that such spinners, under the right circumstances, could be used for centrifugation under circumstances where reliably operating a centrifuge, for  whatever reason, is a challenge.
Read More
Immune cell density plot
Reversal of ApoE4tune

Germline ApoE variants affect melanoma trajectory

May 27, 2020
By Anette Breindl
Variants in the APOE gene are the strongest genetic risk factor for developing Alzheimer’s disease (AD). Now, researchers at Rockefeller University have demonstrated that APOE variants also affected the risk of progression and metastasis as well as the response to immunotherapy, in melanoma.
Read More

BioWorld MedTech’s Orthopedics Extra for May 27, 2020

May 27, 2020
By Holland Johnson
Keeping you up to date on recent developments in orthopedics, including: Cell 'pores' discovery gives hope to millions of brain and spinal cord injury patients; Little skates could hold the key to cartilage therapy in humans; Spinal cord injury increases risk for mental health disorders.
Read More
Genome illustration

Gnomad identifies rare loss of function variants

May 27, 2020
By Nuala Moran
LONDON – A vast new body of genomics research has identified thousands of rare genetic variants that are predicted to cause loss of function in protein coding genes, providing novel in vivo models of human gene inactivation.
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BioWorld MedTech’s Oncology Extra for May 26, 2020

May 26, 2020
By Mark McCarty and Anette Breindl
Keeping you up to date on recent developments in oncology, including: Optoacoustic mesoscopy offers three-dimensional tumor imaging without biopsy; P53 loss leads to immune evasion; Treatment less toxic for Burkitt lymphoma.
Read More
Immune cell density plot
Reversal of ApoE4tune

Germline ApoE variants affect melanoma trajectory

May 26, 2020
By Anette Breindl
Variants in the APOE gene are the strongest genetic risk factor for developing Alzheimer’s disease (AD). Now, researchers at Rockefeller University have demonstrated that APOE variants also affected the risk of progression and metastasis as well as the response to immunotherapy, in melanoma.
Read More

BioWorld MedTech’s Neurology Extra for May 22, 2020

May 22, 2020
By Andrea Applegate and Anette Breindl
Keeping you up to date on recent developments in neurology, including: Noninvasive brain stimulation controls monkeys' choices; Researchers link gene mutation to autism behaviors; Atherosclerosis, AD meet at the myelin; Early roots of ALS visible in teeth.
Read More
Macrophage illustration

Bench Press for May 22, 2020

May 22, 2020
By Anette Breindl
BioWorld looks at translational medicine, including: SIRPa blockade wakes up macrophages post-infection; Lasting immunity to SARS-CoV-2 looks possible; Atherosclerosis, AD meet at the myelin; T cell aging induces broad senescence; P53 loss leads to immune evasion; Early roots of ALS visible in teeth; SLAPping down MDR gram-negatives; ALK is candidate thinness gene; Can N-BPs become MVP again?
Read More
Neurons in the central amygdala of a mouse brain
New analgesia strategy

Amygdala contains pain suppression circuit

May 22, 2020
By Anette Breindl
Researchers at Duke University have identified a region in the central amygdala – more often thought of as a processing hub for emotions – that could suppress pain when activated.
Read More
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