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BioWorld MedTech’s Neurology Extra for May 29, 2020

May 29, 2020
By Andrea Applegate
Keeping you up to date on recent developments in neurology, including: Vagus nerve research improves stimulation for chronic pain; Restoring nerve-muscle communication in ALS; Biomarkers may help us understand recovery time after concussion; Study: MS risk 29% higher for people living in urban areas.
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Cardiovascular.png

Bench Press for May 29, 2020

May 29, 2020
By Anette Breindl
BioWorld looks at translational medicine, including: iPSC microtissue gives clues to heart disease; Tumor types have distinct microbiomes; Kinase helps prepare pre-metastatic niche; EZH2 has dual role; New alcohol risk genes in Caucasians; Assay system identifies mitochondria-targeting drugs for PD; Imitating ticks to evade immunity; Ovarian organoids implicate oviducts.
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BioWorld MedTech’s Diagnostics Extra for May 28, 2020

May 28, 2020
By Meg Bryant and Anette Breindl
Keeping you up to date on recent developments in diagnostics, including: Double-contrast probe detects tiny tumors on MRI, Identifying risk of ischemic stroke, T cell aging induces broader senescence, ALK is a candidate thinness gene.
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Fidget spinner toy and diagnostic fidget spinner

Centrifugation can be child’s play with fidget spinners

May 28, 2020
By John Fox
Fidget spinners are hand-held toys based on a roller bearing and three weighted lobes, which can spin freely, creating centrifugal force when activated manually. Generating centrifugal force with a fidget spinner takes neither electricity nor trained staff. And that has suggested to several researchers that such spinners, under the right circumstances, could be used for centrifugation under circumstances where reliably operating a centrifuge, for  whatever reason, is a challenge.
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Immune cell density plot
Reversal of ApoE4tune

Germline ApoE variants affect melanoma trajectory

May 27, 2020
By Anette Breindl
Variants in the APOE gene are the strongest genetic risk factor for developing Alzheimer’s disease (AD). Now, researchers at Rockefeller University have demonstrated that APOE variants also affected the risk of progression and metastasis as well as the response to immunotherapy, in melanoma.
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BioWorld MedTech’s Orthopedics Extra for May 27, 2020

May 27, 2020
By Holland Johnson
Keeping you up to date on recent developments in orthopedics, including: Cell 'pores' discovery gives hope to millions of brain and spinal cord injury patients; Little skates could hold the key to cartilage therapy in humans; Spinal cord injury increases risk for mental health disorders.
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Genome illustration

Gnomad identifies rare loss of function variants

May 27, 2020
By Nuala Moran
LONDON – A vast new body of genomics research has identified thousands of rare genetic variants that are predicted to cause loss of function in protein coding genes, providing novel in vivo models of human gene inactivation.
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BioWorld MedTech’s Oncology Extra for May 26, 2020

May 26, 2020
By Mark McCarty and Anette Breindl
Keeping you up to date on recent developments in oncology, including: Optoacoustic mesoscopy offers three-dimensional tumor imaging without biopsy; P53 loss leads to immune evasion; Treatment less toxic for Burkitt lymphoma.
Read More
Immune cell density plot
Reversal of ApoE4tune

Germline ApoE variants affect melanoma trajectory

May 26, 2020
By Anette Breindl
Variants in the APOE gene are the strongest genetic risk factor for developing Alzheimer’s disease (AD). Now, researchers at Rockefeller University have demonstrated that APOE variants also affected the risk of progression and metastasis as well as the response to immunotherapy, in melanoma.
Read More

BioWorld MedTech’s Neurology Extra for May 22, 2020

May 22, 2020
By Andrea Applegate and Anette Breindl
Keeping you up to date on recent developments in neurology, including: Noninvasive brain stimulation controls monkeys' choices; Researchers link gene mutation to autism behaviors; Atherosclerosis, AD meet at the myelin; Early roots of ALS visible in teeth.
Read More
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