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BioWorld MedTech’s Cardiology Extra for June 22, 2020

June 22, 2020
By Liz Hollis
Keeping you up to date on recent developments in cardiology, including: App helps to detect fluid in the lungs in HF patients; Connection between opioids and heart surgery; 3D map of heart’s neurons.
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CAR T cells attacking senescent cells

CAR T cells target senescence marker, ameliorate cancer, fibrosis

June 19, 2020
By Anette Breindl
By targeting chimeric antigen receptors (CARs) to a senescence marker, researchers at Memorial Sloan-Kettering Cancer Center have developed a CAR T cell that had beneficial effects in mouse models of both liver fibrosis and lung cancer.
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BioWorld MedTech’s Neurology Extra for June 19, 2020

June 19, 2020
By Andrea Applegate
Keeping you up to date on recent developments in neurology, including: High-resolution 3D model reveals similarity in Alzheimer's, diabetes; New MRI test shows promise in detecting CTE in football players; Neuropointdx reports metabolic biomarker found in children with ASD.
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Foundation CDx1

Second tumor-agnostic approval (further) broadens Keytruda’s reach

June 19, 2020
By Anette Breindl
On June 17, the FDA approved checkpoint blocker Keytruda (pembrolizumab, Merck & Co. Inc.) “for the treatment of adult and pediatric patients with unresectable or metastatic tumor mutational burden-high (TMB-H) [?10 mutations/megabase (mut/Mb)] solid tumors, as determined by an FDA-approved test, that have progressed following prior treatment and who have no satisfactory alternative treatment options.” 
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Human anatomy

Bench Press for June 19, 2020

June 19, 2020
By Anette Breindl
BioWorld looks at translational medicine, including: Liver-derived protein helps lung, kidney repair; Multiracial study gives new diabetes insights; New way to target drugs, independently of drug target; Microbiome-produced metabolites improve gut health; Universal flu vaccine more challenging than anticipated; The bow ties that bind; FOXO1 regulates HIV latency; Patient genetic variants linked to wound microbiomes; New COPD target.
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BioWorld MedTech’s Diagnostics Extra for June 18, 2020

June 18, 2020
By Meg Bryant and Anette Breindl
Keeping you up to date on recent developments in diagnostics, including: Improving diagnosis of pulmonary hypertension; A web-based COVID-19 assessment tool; Discovering pharmacological enzyme activators.
Read More
CAR T cells attacking senescent cells

CAR T cells target senescence marker, ameliorate cancer, fibrosis

June 17, 2020
By Anette Breindl
By targeting chimeric antigen receptors (CARs) to a senescence marker, researchers at Memorial Sloan-Kettering Cancer Center have developed a CAR T cell that had beneficial effects in mouse models of both liver fibrosis and lung cancer.
Read More

BioWorld MedTech’s Orthopedics Extra for June 17, 2020

June 17, 2020
By Holland Johnson
Keeping you up to date on recent developments in orthopedics, including: Osteoporosis treatment also may protect against pneumonia; Study finds similar short-term outcomes after common MI spine procedures; New biomaterial has potential to repair damaged bone with lower risk of inflammation; Diabetics face greater risk of bone fractures.
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Sleep cartoon
Sleepless in Cambridge

Sleep deprivation kills through punch to the gut

June 16, 2020
By Anette Breindl
The disconnect between the need for sleep and the possession of a brain is what prompted Dragana Rogulja, an assistant professor of neurobiology in the Blavatnik Institute at Harvard Medical School, and her team to take a look at multiple tissues in sleep-deprived flies and mice.
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BioWorld MedTech’s Oncology Extra for June 16, 2020

June 16, 2020
By Mark McCarty
Keeping you up to date on recent developments in oncology, including: 3D-printed reservoir + magnetic sponge = new way to beat cancer; HRAS-driven translation helps skin prevent tumors; NETS and mets; Observational study supports cryoablation for RCC.
Read More
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