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BioWorld - Friday, December 19, 2025
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BioWorld Science, Infection
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Colorized transmission electron micrograph of yellow fever virus particles.
Infection

Mabloc and Instituto Butantan partner on MBL-YFV-01

Nov. 19, 2025
No Comments
Mabloc LLC has established a strategic partnership with Instituto Butantan to co-develop and manufacture MBL-YFV-01, a monoclonal antibody therapy for yellow fever virus (YFV) infection, including emergency post-exposure use.
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Microbiome illustration
Dental

‘Most complete’ map of oral microbiome enables links to systemic disease

Nov. 18, 2025
By Marian (YoonJee) Chu
No Comments
South Korean researchers led by Lee In-suk of Yonsei University have reported the most complete oral microbiome catalog to date, with more than 72,000 genomes. Detailed in Cell Host & Microbe on Nov. 12, 2025, the database is expected to serve as a universal platform for academia and enable “precision microbiome medicine” for the industry, Lee told BioWorld.
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Test tubes, dropper and capsules
Infection

Scynexis fungerps among funding recipients

Nov. 18, 2025
No Comments
Scynexis Inc. has announced that a novel series of antifungal compounds utilizing its proprietary triterpenoid antifungal platform are among five projects funded by a federal grant awarded to the new accelerator consortium led by researchers from Hackensack Meridian Center for Discovery and Innovation (CDI) and the Johns Hopkins Bloomberg School of Public Health.
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Gloved hand holding petri dish in lab
Infection

GSK and Fleming Initiative announce AMR research programs

Nov. 18, 2025
No Comments
GSK plc and the Fleming Initiative have announced six major new research programs to find new ways to slow the progress of antimicrobial resistance (AMR). The Fleming Initiative is a collaboration established by Imperial College London and Imperial College Healthcare NHS Trust to help tackle AMR. Each of the new programs will begin by early next year and are fully funded for 3 years.
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Infection

Synergistic antiviral efficacy of HEC-191834 with siRNA in HBV models

Nov. 18, 2025
No Comments
In preclinical studies at Sunshine Lake Pharma Co. Ltd., researchers investigated the antiviral and immune-modulatory potential of HEC-191834, a novel and highly selective human Toll-like receptor 8 (TLR8) agonist, in chronic hepatitis B virus (HBV) models, as well as its activity when combined with siRNA.
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Infection

Assembly Biosciences divulges new viral replication inhibitors

Nov. 17, 2025
Assembly Biosciences Inc. has synthesized viral replication inhibitors reported to be useful for the treatment of herpes viral infections.
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Infection

Anti-malarial targets P. falciparum phosphatidylinositol 4-kinase with reduced toxicity

Nov. 14, 2025
No Comments
In an effort to generate an effective and safer inhibitor, researchers at the University of Cape Town, University of Dundee and Massachusetts Institute of Technology used structure-guided rational design to improve on their previously reported 2,8-diaryl-1,5-naphthyridine inhibitor.
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Immune

Dual-antigen mRNA vaccine protects against lethal DBV challenge

Nov. 13, 2025
No Comments
Investigators from the University of Science and Technology of China and RNAlfa Biotech have described a novel mRNA-based vaccine candidate against Dabie Banda virus (DBV), which has fatality rates of up to 30% in some East Asian countries.
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Microbiome illustration
Dental

‘Most complete’ map of oral microbiome enables links to systemic disease

Nov. 13, 2025
By Marian (YoonJee) Chu
No Comments
South Korean researchers led by Lee In-suk of Yonsei University have reported the most complete oral microbiome catalog to date, with more than 72,000 genomes. Detailed in Cell Host & Microbe on Nov. 12, 2025, the database is expected to serve as a universal platform for academia and enable “precision microbiome medicine” for the industry, Lee told BioWorld.
Read More
Infection

Aligos and KU Leuven divulge new antivirals

Nov. 10, 2025
Aligos Therapeutics Inc. and Katholieke Universiteit Leuven (KU Leuken) have synthesized antiviral compounds reported to be useful for the treatment of coronavirus acute respiratory syndrome, norovirus and picornavirus infections.
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