Nextcure Inc. won’t advance the non-small-cell lung cancer (NSCLC) and ovarian cancer cohorts in the stage two portion of its phase I/II study of NC-318, a monoclonal antibody targeting Siglec-15 (S15), as a monotherapy. The data and decision prompted the company stock to shed more than half its value July 13 and several analysts to adjust their price targets downward.
Although details are yet to come, Equillium Inc.’s chief medical officer, Krishna Polu, told BioWorld that the company will move “urgently and expeditiously” to set up another experiment testing itolizumab in COVID-19 now that Bangalore, India-based partner Biocon Ltd. has unveiled positive phase II results with the CD6-targeting agent.
CAJICA, Colombia, and BEIJING – Last week Sinovac Biotech Ltd., of Beijing, announced the approval by Anvisa, the Brazilian health care surveillance agency, to start phase III trials to test the efficacy and safety of its inactivated COVID-19 vaccine being developed by Sinovac Life Sciences, a subsidiary of the Chinese company, in the Latin American country.
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Abeona, Atox, Center Laboratories, DBV, Gilead, Macrogenics, Sedana, Sosei, Tonix, Ziopharm.
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Acer, Bayer, Biogen, Enanta, Ideaya, JS Innopharm.
Bharat Biotech International Ltd. has successfully developed India’s first indigenous vaccine candidate for COVID-19 to enter human trials. Named Covaxin, the vaccine has been cleared by the Drug Controller General of India (DCGI) and Ministry of Health & Family Welfare for phase I and II trials after the company submitted positive preclinical study results regarding safety and immune response.
Corvus Pharmaceuticals Inc.’s success in treating a COVID-19 patient previously diagnosed with non-small-cell lung cancer (NSCLC) with CPI-006 helped boost shares (NASDAQ:CRVS) to $4.96, up $2.21, or 181%, as the Burlingame, Calif.-based company disclosed the start of a phase I study to investigate the anti-CD73 immunotherapy prospect.
RSS
