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BioWorld - Wednesday, February 11, 2026
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Fingerprints in shape of lungs with magnifying glass and DNA

As targeted options expand, making the best match, and the most matches

Sep. 17, 2021
By Anette Breindl
Researchers have retrospectively divided more than 16,000 non-small-cell lung cancer (NSCLC) patients with EGFR mutations into four structure-based subgroups, and looked at how the members of each subgroup fared depending on which EGFR inhibitor they were given.
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KRAS protein

KRAS just wants to help: Pancreatic KRAS mutations may be protection gone bad

Sep. 17, 2021
By Anette Breindl
Investigators at MD Anderson Cancer Center have published data suggesting that activating KRAS mutations may be selected for in pancreatitis, because they protect pancreatic tissue from damage.
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Brain and blood cells

Blood-to-brain pathway may deliver amyloids in Alzheimer's disease

Sep. 16, 2021
By Tamra Sami
Researchers at Curtin University in Perth, Australia, have discovered that leakage from blood into the brain of fat-carrying particles transporting toxic proteins are a possible cause of Alzheimer's disease.
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Brain and encephalography

Targeting late inflammation via complement system ameliorates TBI-induced epilepsy

Sep. 15, 2021
By W. Todd Penberthy
Investigators working at Gladstone Institutes reported new insights into sleep disturbances and seizures that can be a late consequence of even mild traumatic brain injuries (TBI), and how we may one day best treat these conditions by targeting the complement pathway.
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E-health patch on skin

Austro-Japanese team developing e-health patches that can monitor pulse and blood pressure

Sep. 14, 2021
By Bernard Banga
PARIS – Researchers at the Institute for Surface Technologies and Photonics in Weiz, Austria, and the Institute of Scientific and Industrial Research Osaka University, Japan, have invented new ultra-flexible health monitoring patches that use harvested bio-mechanical energy. “These new devices represent a wireless e-health patch for accurate pulse and blood pressure monitoring,” Andreas Petritz, from the Institute for Surface Technologies and Photonics (the materials research unit of Joanneum Research FmbH), told BioWorld.
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Elderly hands holding broken brain structure

Metabolomics study reveals dementia-linked metabolites

Sep. 14, 2021
By John Fox
A comprehensive nontargeted metabolomics analysis has revealed previously unknown classes of disease-linked metabolites in whole blood samples from dementia patients, which may have significant therapeutic implications for managing the untreatable common cognitive disorder.
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Chromosomes

Pre-existing chromosomal instability may predict response to paclitaxel

Sep. 14, 2021
By Subhasree Nag
In a recent study, researchers led by Beth Weaver from the University of Wisconsin, Madison (UW-M) show that paclitaxel treatment in breast cancer patients increased cell division with chromosome missegregation to induce cytotoxicity.
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Elderly hands holding broken brain structure

Metabolomics study reveals dementia-linked metabolites

Sep. 13, 2021
By John Fox
A comprehensive nontargeted metabolomics analysis has revealed previously unknown classes of disease-linked metabolites in whole blood samples from dementia patients, which may have significant therapeutic implications for managing the untreatable common cognitive disorder.
Read More
Elderly hands holding broken brain structure

Metabolomics study reveals dementia-linked metabolites

Sep. 13, 2021
By John Fox
A comprehensive nontargeted metabolomics analysis has revealed previously unknown classes of disease-linked metabolites in whole blood samples from dementia patients, which may have significant therapeutic implications for managing the untreatable common cognitive disorder.
Read More
Lung cancer illustration

At WCLC, early steps toward success against SCLC

Sep. 10, 2021
By Anette Breindl
Driven by advances in scientific understanding, the treatment of non-small-cell lung cancer (NSCLC) has begun to see successes one subtype at a time. At the 2021 World Conference on Lung Cancer (WCLC), which is currently being held in virtual format, researchers were optimistic that the same path would be possible for small-cell lung cancer (SCLC).
Read More
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