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The skinny on the Laskers: GLP-1 innovators honored

Sep. 24, 2024
By Lee Landenberger
An innovation that has kickstarted a revolution in the study and practice of health care is getting even more attention. Three scientists who pioneered the discovery and development of glucagon-like peptide-1 (GLP-1)-based obesity treatments have been named 2024 Lasker Award winners.
Read More
CAR T cell with implanted gene strand

ECTRIMS 2024: Driving a fast CAR on the MS road and beyond

Sep. 23, 2024
By Coia Dulsat
Chimeric antigen receptor (CAR) T-cell therapy moved the needle at the 2024 ECTRIMS (European Committee for Treatment and Research in Multiple Sclerosis) congress and will continue to do so – not just in multiple sclerosis (MS), but in other autoimmune diseases as well.
Read More
3D rendering of glucagon-like peptide 1 (GLP-1)
Endocrine/metabolic

The skinny on the Laskers: GLP-1 innovators honored

Sep. 23, 2024
By Lee Landenberger
An innovation that has kickstarted a revolution in the study and practice of health care is getting even more attention. Three scientists who pioneered the discovery and development of glucagon-like peptide-1 (GLP-1)-based obesity treatments have been named 2024 Lasker Award winners.
Read More

The skinny on the Laskers: GLP-1 innovators honored

Sep. 20, 2024
By Lee Landenberger
An innovation that has kickstarted a revolution in the study and practice of health care is getting even more attention. Three scientists who pioneered the discovery and development of glucagon-like peptide-1 (GLP-1)-based obesity treatments have been named 2024 Lasker Award winners.
Read More
Fallopian tubes, ovaries and uterus
Aging

Preventing fibrosis early extends ovarian health

Sep. 20, 2024
By Anette Breindl
By treating mice with antifibrotic drugs, researchers were able to stave off functional decline of the ovaries. Six weeks of systemic treatment with the antifibrotic pirfenidone, which is approved for the treatment of idiopathic pulmonary fibrosis, in early middle age improved both the morphology and the endocrine function of the animals’ ovaries at 1 year of age.
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Juleen Zierath on stage at EASD 2024
Endocrine/metabolic

Studies on exercise and health win EASD prize

Sep. 19, 2024
By Mar de Miguel
How do exercise and insulin collaborate in metabolism? The European Association for the Study of Diabetes (EASD) and the Novo Nordisk Foundation recognized the work of Juleen Zierath in this topic with the Diabetes Prize for Excellence at their recent annual meeting.
Read More
Brain waves
Neurology/psychiatric

ECTRIMS 2024: Time for neuroprotection

Sep. 19, 2024
By Coia Dulsat
The Annual Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) meeting in Copenhagen this week is celebrating its 40th edition. In recognition of this landmark, the plenary session and opening lecture were attended by Queen Margrethe of Denmark. Afterward, the hot topic session on neuroprotective therapies set the stage for the subsequent discussions on the latest trends in the management and treatment of multiple sclerosis (MS).
Read More
Juleen Zierath on stage at EASD 2024
Endocrine/metabolic

Studies on exercise and health win EASD prize

Sep. 18, 2024
By Mar de Miguel
How do exercise and insulin collaborate in metabolism? The European Association for the Study of Diabetes (EASD) and the Novo Nordisk Foundation recognized the work of Juleen Zierath in this topic with the Diabetes Prize for Excellence at their recent annual meeting.
Read More
AI-generated illustration of Claudin proteins

ESMO 2024: Cancer vaccines can boost antitumor immunity

Sep. 17, 2024
By Anette Breindl
One of the current challenges of immunotherapy is the hunt for good targets, and the Claudins – a family of roughly two dozen transmembrane proteins – would appear to have a lot going for them. “Some Claudins distribute in a tissue-specific manner, and malignant transformation causes their exposition,” Cinta Hierro told the audience at the European Society of Medical Oncology (ESMO) 2024 Congress. “Others are rarely expressed in healthy tissue.”
Read More
Cancer cells under magnifying glass
Cancer

ESMO 2024: For T-cell target antigens, lots to see, but what to show?

Sep. 16, 2024
By Anette Breindl
Metastatic solid tumors may be curable now. Among the most profound results presented over the weekend at the European Society for Medical Oncology (ESMO) 2024 Congress were the 10-year data from the Checkmate-067 and Keynote-006 trials, the phase III trials that tested Opdivo (nivolumab, Bristol Myers Squibb Co.) and Keytruda (pembrolizumab, Merck & Co. Inc.) as first-line agents in advanced or metastatic melanoma.
Read More
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