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BioWorld - Monday, December 22, 2025
Home » Topics » Clinical

Clinical
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Cells infected with SARS-CoV-2

COVID-19: Study points to kinases as HIV combo falls flat for SARS-CoV-2

June 29, 2020
By Nuala Moran
LONDON – Scientists investigating the impact of SARS-CoV-19 on protein expression in human cells have shown that infected cells develop virus-laden membrane protrusions, or filopodia, which may explain the rapidity of viral spread through the body.
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Illustration of device in artery

Elixir Medical sees positive data for adaptive remodeling coronary stent technology

June 29, 2020
By Meg Bryant
Elixir Medical Corp., reported positive 12-month results for its Dynamx Coronary Bioadaptor System, with no target vessel revascularization (TVR) or stent thrombosis and adaptive remodeling of the artery to sustain healthy blood flow. The findings, from a multisite European trial, were presented during a late-breaking trials session at the PCR e-Course virtual meeting in Paris.
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Product image

Abbott rolls out slew of data on minimally invasive structural heart implants

June 26, 2020
By Stacy Lawrence
Minimally invasive structural heart implants are moving from mitral into tricuspid valve repair, as well as mitral valve replacement. Abbott Laboratories is presenting its latest data on all these fronts at the virtual PCR e-Course held by the European Association of Percutaneous Cardiovascular Interventions from June 25 to 27.
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China moves two more COVID-19 vaccines to trials, another one entering phase III

June 26, 2020
By Elise Mak
BEIJING – China this week approved both the country’s first mRNA vaccine candidate and its first recombinant protein subunit vaccine to begin clinical trials to fight COVID-19.
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In the clinic for June 26, 2020

June 26, 2020
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Highlight, Janssen, Onconano.
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In the clinic for June 25, 2020

June 25, 2020
Clinical updates, including trial initiations, enrollment status and data readouts and publications: 9 Meters, Acceleron, Adial, Aiviva, Algernon, Assembly, Astrazeneca, Bergenbio, Geneuro, Insmed, Kiadis, Moberg, Neoimmunetech, Novan, Noxopharm, Oncolytics, Theravance.
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Side and top view of Epygon valve

Affluent Medical kicks off first-in-human trial of Epygon valve

June 24, 2020
By Meg Bryant
French startup Affluent Medical SA has launched a European pilot study in humans of its native-like transcatheter mitral valve technology. The Epygon valve is designed to restore the normal blood flow vortex in the left side of the heart and treat left ventricle disease, particularly in so-called “functional” patients.
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Despite missing primary outcome measure, Biohaven plans to move troriluzole into phase III

June 24, 2020
By Lee Landenberger
While Biohaven Pharmaceutical Holding Co. Ltd.’s phase II/III proof-of-concept study of troriluzole for treating obsessive-compulsive disorder (OCD) failed to meet its primary outcome measure at week 12, the company found enough silver in the study’s lining to press on for a larger phase III trial.
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Opaganib bottle and tablets

Yeliva see anything: Redhill calls out opaganib’s promise in COVID-19

June 24, 2020
By Randy Osborne
Redhill Biopharma Ltd.’s chief operating officer, Gilead Raday, told BioWorld that the firm will build on positive results in severe COVID-19 patients with oral opaganib, a first-in-class sphingosine kinase-2 inhibitor.
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Australia’s Cynata ahead of the pack as it progresses iPSCs to phase III osteoarthritis trial

June 24, 2020
By Tamra Sami
PERTH, Australia – Melbourne-based regenerative medicine company Cynata Therapeutics Ltd. is gearing up to take its Cymerus mesenchymal stem cell (MSC) product candidate, CYP-004, into a phase III trial in osteoarthritis.
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