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BioWorld - Thursday, March 19, 2026
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BioWorld MedTech’s Diagnostics Extra for April 22, 2021

April 22, 2021
By Meg Bryant
Keeping you up to date on recent developments in diagnostics, including: AI-based model to triage brain MRIs; Tiny light probes enhance brain imaging; Predicting natural menopause age.
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Bench Press

Autophagy chaperone targets aggregation-prone proteins

April 22, 2021
By Anette Breindl
BioWorld looks at translational medicine, including: Pharmacological target for anorexia.
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PCSK9 affects antitumor immunity

April 22, 2021
By Anette Breindl
The enzyme proprotein convertase subtilisin/kexin type 9 (PCSK9) plays a major role in the regulation of blood LDL cholesterol levels. Now, new research shows that targeting PCSK9 may also potentiate checkpoint blockade.
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Bioelectronics next to penny

Feinstein team develops long-term vagus nerve stimulation model

April 21, 2021
By Annette Boyle
A team led by researchers at the Institute of Bioelectronic Medicine at The Feinstein Institutes for Medical Research, the research division of New York’s Northwell Health, developed a long-term implant model for vagus nerve stimulation (VNS) in mice that enables study of bioelectronics in chronic disease. The research was published in Elife, with a full description of the surgical technique and methods for calibrating the stimulation dose to enable other labs to use the methods to advance bioelectronic medicine.
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BioWorld MedTech’s Orthopedics Extra for April 21, 2021

April 21, 2021
By Holland Johnson
Keeping you up to date on recent developments in orthopedics, including: 3D biomaterial used as 'sponge' for stem cell therapy to reverse arthritis; New biomaterial regrows blood vessels and bone, RCSI research; Without major changes, gender parity in orthopedic surgery will take two centuries.
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Silhouettes

SEP-363856 is associated with robust improvement in negative symptoms of schizophrenia

April 21, 2021
Researchers from Sunovion Pharmaceuticals Inc. presented early clinical data for SEP-363856, a novel trace amine receptor 1 agonist with serotonin 5-HT1A activity, being developed for the treatment of patients with schizophrenia.
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BioWorld MedTech’s Oncology Extra for April 20, 2021

April 20, 2021
By Mark McCarty
Keeping you up to date on recent developments in oncology, including: Research may enable real-time imaging of tumors during PBT treatments; Algorithm may restore raw mammograms from processed images; Hand-held device would check for PSA.
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Stem cells

New technique casts light on stem cell differentiation

April 20, 2021
By John Fox
Researchers at the Walter and Eliza Hall Institute for Medical Research in Melbourne, Australia, have used a newly developed single-cell clonal multiomics technique to gain a better understanding of the genetic programming underlying how stem cells differentiate into particular cell types.
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BioWorld MedTech’s Cardiology Extra for April 19, 2021

April 19, 2021
By Mark McCarty
Keeping you up to date on recent developments in cardiology, including: PCI still the treatment of choice for COVID-positive STEMI patients; Utility of risk scores for TAVR patients questioned; Plaque similarly predictive in women and men.
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Brain, illustrating pain/injury

Brain injury modulates bone marrow cells to reduce neuroinflammation

April 19, 2021
By John Fox
Chinese neuroscientists have identified a bone marrow (BM) response to acute brain injury, in which the fate and function of BM hematopoietic cells are shaped by brain injury, suggesting that the brain can mobilize a population of protective monocytes and direct them to the injury site.
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