Two separate groups have recently shown that in mouse models, inactivation of a single gene was enough to directly convert other cell types in the brain into neurons.
Chinese scientists at Peking University (PKU) in Beijing have developed a new in vitro patient-derived tumor-like cluster (PTC) model, which predicted the outcomes of neoadjuvant and conventional chemotherapies in colon, gastric and breast cancer patients, with a clinical consistency of >93%.
LONDON – Scientists investigating the impact of SARS-CoV-19 on protein expression in human cells have shown that infected cells develop virus-laden membrane protrusions, or filopodia, which may explain the rapidity of viral spread through the body.
Keeping you up to date on recent developments in cardiology, including: COVID-19 an independent risk factor for acute ischemic stroke; New heart valve holds hope for open heart surgery; Company unveils results on therapy to treat cardiovalvular diseases.
Technical challenges at the annual meeting of the International Society for Stem Cell Research (ISSCR) meeting led to at least one lively exchange of stem cell jokes in the chat box as the audience waited for talks to resume, including stem cell parental advice: “You can be anything you want when you grow up!”
Keeping you up to date on recent developments in neurology, including: A focused approach to imaging neural activity in the brain; International study discovers 3 potential new targets for treating epilepsy; New genetic mutations linked to ASD; Alzheimer’s study finds higher risk of disease in women vs. men due to hormones.
BioWorld looks at translational medicine, including: A Tau-sand forms of tau?; P53 ‘glue’ gums up cancer cells; Shock and kill with less toxicity; Placental attachment theory.
Keeping you up to date on recent developments in diagnostics, including: Border detection algorithm for melanoma; Predicting future suicide risk; Multiracial study gives new diabetes insights; Patient genetic variants linked to wound microbiomes.
Keeping you up to date on recent developments in orthopedics, including: Nuclear softening allows cells to move into dense tissue, encouraging injury repair; 3D X-ray reveals secrets from inside bones; Fantastic muscle proteins and where to find them.
By targeting chimeric antigen receptors (CARs) to a senescence marker, researchers at Memorial Sloan-Kettering Cancer Center have developed a CAR T cell that had beneficial effects in mouse models of both liver fibrosis and lung cancer.
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